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3689 results

Full text 2025

Genomic surveillance and phylo-evolutionary analysis of SARS-CoV-2 variants in Osun state, Nigeria during the second wave of COVID-19 pandemic

Akinde SB, Oyedara OO, Olumakinde TS, et al.

BACKGROUND: SARS-CoV-2 genome sequencing, genomic characterization, and global data sharing are recommended to facilitate countermeasures against COVID-19. This study involved whole genome sequencing and phylo-evolutionay analysis of SARS-CoV-2 variants circulating in Osun State, Nigeria between …

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Bioinformatics
Full text 2026

Phylogenomic diversity of clinical <i>Saccharomyces cerevisiae</i> and the prevalence of probiotic-derived isolates in a tertiary care center in Hungary

Harmath A, Németh B, Pócsi I, et al.

<i>Saccharomyces cerevisiae</i> is traditionally considered a non-pathogenic microbe; however, recent evidence has established its role as an opportunistic fungal pathogen. The probiotic subtype, var. "<i>boulardii</i>," is widely administered for the prevention and treatment of gastrointestinal …

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Bioinformatics
Full text 2026

Comparative genomics reveals synteny-guided remodeling of carbohydrate-foraging and intrinsic resistance in an ocular Chryseobacterium isolate, NG-CE01

Hassan F, Türkyılmaz S, El-Mahdy TS.

BACKGROUND: Chryseobacterium spp. are environmentally widespread bacteria increasingly recognized as opportunistic pathogens in human and veterinary medicine, yet genome-scale determinants that may support persistence in host-associated microenvironments remain poorly defined. Isolates from anatomically specialized sites …

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Bioinformatics
Full text 2026

Integrated Phylogenomics and Expression Profiling of the Peptide Deformylase Gene Family in &lt;i&gt;Oryza sativa&lt;/i&gt; Reveals Their Role in Development and Stress Tolerance

Yuan C, Zhang Y, Zhao M, et al.

Peptide deformylase (PDF) belongs to a conserved enzyme family critical for N-terminal methionine excision (NME), an essential protein maturation process in prokaryotes and eukaryotic organelles (chloroplasts, mitochondria). To explore the potential functions of <i>OsPDFs</i> in …

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Bioinformatics
Full text 2026

Characterization of a conjugative IncFII/IncR plasmid harboring bla&lt;sub&gt;KPC-2&lt;/sub&gt; in a clinical ST91 Citrobacter freundii isolate

Liu X, Liu Z, Sun Z, et al.

BACKGROUND: Carbapenem-resistant Citrobacter freundii is increasingly reported and recognized as an opportunistic host of mobile carbapenemase-encoding elements in healthcare-associated settings. However, lineage-associated plasmid vehicles and their transfer-related features in this species remain incompletely characterized. OBJECTIVE: …

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Bioinformatics