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Full text 2025

Chromosome-level genome assembly of Hippophae salicifolia

Zeng Z, Mao C, Zhang J, et al.

Hippophae salicifolia, a dioecious small tree species endemic to the Himalayan region, holds great potential in both ecological conservation and industrial applications. In this study, we employed PacBio HiFi long reads, Illumina short reads, and …

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Genome Assembly Nanopore Sequencing
Full text 2025

Reference-based chromosome-scale assembly of Japanese barley (Hordeum vulgare ssp. vulgare) cultivar Hayakiso 2

Tanaka T, Haraguchi Y, Todoroki T, et al.

Current advances in next-generation sequencing (NGS) technology and assembling programs permit construct chromosome-level genome assemblies in various plants. In contrast to resequencing, the genome sequences provide comprehensive annotation data useful for plant genetics and breeding. …

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Genome Assembly Nanopore Sequencing
Full text 2025

Beyond single references: pangenome graphs and the future of genomic medicine

Nyaga DM, Zaied RE, Silander OK, et al.

Genomic medicine relies on single reference genomes that miss crucial genetic diversity, creating diagnostic gaps that disproportionately affect underrepresented populations. Pangenome graphs, collections of diverse genomes represented as interconnected genetic paths, offer a powerful alternative …

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Genome Assembly Nanopore Sequencing Structural Variants
Full text 2025

The genome sequence of the Alpine Milkvetch, <i>Astragalus alpinus</i> L. (Fabales: Fabaceae)

Ruhsam M, Hollingsworth PM, Royal Botanic Garden Edinburgh Genome Acquisition Lab, et al.

We present a genome assembly of <i>Astragalus alpinus</i> (Alpine Milkvetch; Streptophyta; Magnoliopsida; Fabales; Fabaceae). The assembly consists of two haplotypes with total lengths of 766.58 megabases and 749.43 megabases. Most of haplotype 1 (98.55%) and …

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Genome Assembly