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<h4>Background</h4>While evidence linking the gut microbiome (GM) to cancer immunotherapy is growing, data regarding its role in chemotherapy remains limited. This study aims to investigate the effect of chemotherapy on GM composition and its potential …
Read PDF[This corrects the article DOI: 10.3389/fmicb.2026.1800013.].
Read PDFThe genus <i>Kluyvera</i> (<i>Enterobacteriaceae</i>) comprises gram-negative, motile, non-spore-forming rods. <i>Kluyvera sichuanensis</i> strain 142937 was isolated in this study from biliary drainage fluid. The draft genome sequence of this clinical strain was determined to be approximately …
Read PDFMultiple germline and somatic genomic factors are associated with risk of coronary artery disease, but there is no single measure of risk that integrates all information from a DNA sample. To address this gap, we …
Read PDFIn this commentary, we describe how the Clinical Genome Resource's (ClinGen's) application programming interface-based microservices accelerate growth and dissemination of knowledge about human genetic variation. By exposing findable, accessible, interoperable, reusable, and AI-ready variant data, …
Read PDFThiopurine medications are widely used for the treatment of acute lymphoblastic leukemia and inflammatory bowel disease. However, thiopurine-induced hemotoxicity occurs in up to 30% of patients, which causes substantial morbidity and limits therapeutic success. These …
Read PDFBACKGROUND: Bifid nose with or without anorectal and renal anomalies (BNAR) is a rare autosomal recessive genetic congenital disorder characterized by bifid nose and renal agenesis, with or without anorectal malformations. Our research identified the …
Read PDFThe occurrence of myelodysplastic syndrome (MDS) in children is infrequently documented and most commonly manifests in the form of refractory cytopenia of childhood (RCC). The management of pediatric MDS remains controversial and involves primarily chemotherapy, …
Read PDFPassion fruit (Passiflora edulis) is a highly nutritious horticultural crop cultivated widely across tropical and subtropical regions. Despite decades of breeding efforts that have led to the release of a few high-yielding cultivars, on-farm productivity …
Read PDFFunctional enrichment analysis (FEA) is an incredibly powerful way to summarise complex genomics data into information about the regulation of biological pathways including cellular metabolism, signalling and immune responses. About 10,000 scientific articles describe using …
Read PDFAdvances in genomics have transformed histopathology, especially in oncology teaching. Histopathologists traditionally assess tissue morphology, but now integrate genomic data to enhance diagnostic accuracy and treatment precision. Students must grasp both disciplines and appreciate the …
Read PDFThis report presents the draft genome sequence of a lactic acid bacterium, <i>Limosilactobacillus fermentum</i> PJG11, isolated from wild yam, <i>Dioscorea luzonensis</i>, an endemic root crop in Ilocos Norte, Philippines. The discovered genomic characteristics of the …
Read PDFUnderstanding how dispersal, life history, and environmental variability shape genetic connectivity in the open ocean remains a central challenge in evolutionary biology. Highly migratory marine predators like tunas have traditionally been considered genetically homogeneous across …
Read PDFBACKGROUND: The Clinical Genomics & Genomic Medicine Education subcommittee of the Human Genome Organization (HUGO) reports on the results of an exploratory genomic medicine survey of healthcare providers (clinicians) in low- and middle-income countries. RESULTS: …
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