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Full text 2026

Draft genome sequence of <i>Enterobacter asburiae</i> strain P67 isolated from fecal specimen of a <i>Helicobacter pylori</i>-infected male patient of Sikkim, India

Padhi S, Sarkar P, Sharma T, et al.

We report here the draft genome sequence of an <i>Enterobacter asburiae</i> strain P67, sequence type 252 (ST252), isolated from a fecal specimen of a <i>Helicobacter pylori</i>-infected male patient from Sikkim, India. The genome was 4,731,308 …

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Bioinformatics
Full text 2025

ntSynt: multi-genome synteny detection using minimizer graph mappings

Coombe L, Kazemi P, Wong J, et al.

<h4>Background</h4>With the growing availability of reference-grade genome assemblies across diverse taxa, there is an increasing need for efficient and scalable tools for multi-species comparative genomics, including synteny detection. Here, we introduce ntSynt, a scalable utility …

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Bioinformatics
Full text 2025

SimGBS: a rapid method for simulating large-scale genotyping-by-sequencing data

Kang J, Hess MK, Dodds KG, et al.

BACKGROUND: Genotyping-by-sequencing (GBS) offers a cost-effective solution to access genomic information on many samples. The advent of GBS has promoted large scale genomic analyses, including linkage analysis, heritability estimation, inference of genetic relatedness and genome-wide …

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Bioinformatics
Full text 2025

Multi-metric locality sensitive hashing enhances alignment accuracy of bisulfite sequencing reads: BisHash

Nikaein H, Sharifi-Zarchi A.

<h4>Motivation</h4>Locality-Sensitive Hashing (LSH) is a widely used algorithm for estimating similarity between large datasets in bioinformatics, with applications in genome assembly, sequence alignment, and metagenomics. However, traditional single-metric LSH approaches often lead to inefficiencies, particularly …

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Bioinformatics Metagenomics
Full text 2025

Comparative analysis of cattle (Bos taurus, 2n = 60) and river buffalo (Bubalus bubalis, 2n = 50) genome assemblies reveals two evolutionary conserved inversions and invalid centromere-telomere orientation of some autosomes

Pistucci R, Cascone I, Iannuzzi A, et al.

This study investigates autosome evolution between river buffalo (Bubablus bubalis, BBU) and cattle (Bos taurus, BTA), two closely related species within the Bovidae family. Despite differences in chromosome numbers (2n = 60 in cattle and …

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Bioinformatics Genome Assembly
Full text 2025

Long-read microbial genome assembly, gene prediction and functional annotation: a service of the MIRRI ERIC Italian node

Contaldo SG, d'Acierno A, Bosio L, et al.

<h4>Background</h4>Understanding the structure and function of microbial genomes is crucial for uncovering their ecological roles, evolutionary trajectories, and potential applications in health, biotechnology, agriculture, food production, and environmental science. However, genome reconstruction and annotation remain …

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Bioinformatics Genome Assembly Nanopore Sequencing
Full text 2026

Closely related, yet phenotypically different - Genome assemblies of two sister species of widow spiders: &lt;i&gt;Latrodectus hasselti&lt;/i&gt; and &lt;i&gt;L. katipo&lt;/i&gt;, Theridiidae

Ivanov V, Uludağ KÖ, Schneider JM, et al.

Widow spiders of the genus <i>Latrodectus</i> are important animals for biomedical, pest and conservation research. Here, we present the assembled genomes of two closely related <i>Latrodectus</i> species: the Australian <i>L. hasselti</i> and the New Zealand …

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Bioinformatics