Full text 2025

BacExplorer: an integrated platform for <i>de novo</i> bacterial genome annotation

Privitera GF, Cannata AA, Campanile F, et al.

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Abstract

<h4>Motivation</h4>High-throughput sequencing (HTS) has become an integral part of routine analysis for microbiologists. The process of sequencing dozens of samples generates vast amounts of data that cannot be annotated manually. To address this challenge, numerous tools for bacterial genome analysis have been developed over the years. Using freely available databases, these tools enable users to significantly accelerate their analyses. However, many of these tools require advanced computer science expertise to operate effectively.<h4>Results</h4>To overcome this limitation, we developed BacExplorer. Featuring a user-friendly interface, a locally installable application, and an interactive HTML report, BacExplorer empowers users of all skill levels to perform their own analyses with ease and efficiency.<h4>Availability and implementation</h4>BacExplorer is available at: https://github.com/knowmics-lab/BacExplorer.