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African swine fever (ASF), a highly contagious and lethal viral disease, continues to devastate the global swine industry. The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges for ASF control. …
Read PDFThis paper reports the draft genome sequence of <i>Rhodotorula</i> sp. BUB8, an oleaginous yeast isolated from the forest canopy of Mt. Makiling Forest Reserve in the Philippines. The draft genome is 20,394,133 bp with 64.3% …
Read PDFMHCII-peptide binding plays a vital role in immunology. MHCII molecules are primarily expressed on the surface of antigen presenting cells where they capture and present exogenous antigen peptides to helper T cells, thereby activating humoral …
Read PDFIn 2018, pigeon Rotavirus A G18P[17] was identified in Australia as the causative agent of a disease outbreak presenting as vomiting and diarrhea, reminiscent of the young pigeon disease syndrome. This virus has subsequently been …
Read PDF[This corrects the article DOI: 10.3389/fbinf.2026.1793862.].
Read PDFHere, we report on the draft genomes of five putative biosurfactant-producing isolates of <i>Serratia</i> sp. from the East, West, and South bays of Laguna de Bay, Philippines. The contigs ranged from 20 to 21, and …
Read PDFWe report the complete genome sequence of a polycaprolactone-degrading <i>Bacillus xiamenensis</i> B0331, comprising a 3.78 Mb chromosome and three plasmids (94.67, 6.48, and 5.99 kb). The strain was isolated from dumpsite soil in Bay, Laguna, …
Read PDF<i>Salmonella</i> is a globally prevalent and diverse group of pathogenic bacteria that reside in food animals, such as swine. They possess transmissible antimicrobial resistance (AMR) and virulence factors, causing outbreaks with varying disease outcomes. This …
Read PDFWe report the complete genome sequence (4,727,598 bp chromosome, 308,757 bp plasmid of emerging <i>S</i>. Infantis (pESI), and 5,423 bp pSCD6R1a_5.4k plasmid) of <i>Salmonella enterica</i> serovar Infantis SCD6R1a, isolated from raw chicken meat sold at …
Read PDF<h4>Motivation</h4>Whole-genome sequencing (WGS) is now routinely used for surveillance and outbreak investigations of foodborne pathogens. However, the reliability of downstream analyses strongly depends on sequencing read quality, including depth of coverage and the presence of …
Read PDFThe rapid evolution of artificial intelligence (AI) and its profound integration with the pharmaceutical industry essentially constitute a process of knowledge recombination. Yet, empirical evidence systematically characterizing the structural and evolutionary dynamics of this phenomenon …
Read PDF<h4>Motivation</h4>RNA molecules adopt dynamic ensembles of secondary structures, where the local structural context of each nucleotide-such as whether it resides in a stem or a specific type of loop-strongly shapes molecular interactions and regulatory function. …
Read PDF<h4>Motivation</h4>Haplo2D6 is a free, browser-based tool that automates the translation of <i>CYP2D6</i> genotype data into metabolizer phenotypes. Using haplotype reconstruction with the PHASE algorithm, integration of copy number variation estimates, and curated definitions from ClinPGx …
Read PDF[This corrects the article DOI: 10.3389/frai.2026.1770564.].
Read PDFResearch universities and institutes invest in building core facilities that allow investigators to access the costly instrumentation and specialized expertise needed to perform cutting edge biomedical research. For the past 30 years, the National Institutes …
Read PDF<h4>Background</h4>Sex hormones play critical roles in the pathogenesis and progression of osteoarthritis (OA), yet the hormone-related molecular networks remain poorly defined. This study aimed to identify candidate sex hormone-associated genes in OA and to explore …
Read PDF<h4>Motivation</h4>How population structure can shape genetic diversity is a longstanding problem in population genetics. While the use of geographic locations, when available, can help answer some of these questions, it is still difficult to determine …
Read PDF<h4>Motivation</h4>Predicting the thermodynamic stability of proteins upon single-point mutations is a pivotal step in both protein engineering and medicine. In the study of predicting protein thermodynamic stability, various computational methods, whether they extract features at …
Read PDF<h4>Summary</h4>Liquid biopsy offers a non-invasive approach to study tumor-derived genetic material circulating in plasma. Beyond genetic alterations, the fragmentomic features of cell-free DNA-such as fragment size, genomic position, and end-motifs-provide valuable insights into the biological …
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