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Full text 2026

nTChap: an accurate method for polyploid haplotype reconstruction

Gao Y, Qi J, Yu T, et al.

Haplotypes of polyploid organisms provide important insights into polyploid evolution and advanced breeding strategies. Significant challenges remain in polyploid haplotype phasing, including the great number of haplotype copies and the presence of haplotypes with high …

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Bioinformatics Nanopore Sequencing
Full text 2026

Draft genome sequence of <i>Aliihoeflea</i> sp. strain PC F10.4, isolated from the Antarctic red alga <i>Plocamium cartilagineum</i>

Acevedo W, Mobarec F, Alvarez J, et al.

We present the draft genome sequence of <i>Aliihoeflea</i> strain PC F10.4, an alphaproteobacterium isolated from the surface of the red macroalga <i>Plocamium cartilagineum</i> collected at King George Island, Antarctica. The assembled genome is 4,743,656 bp …

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Bioinformatics
Full text 2026

Complete genome sequence of &lt;i&gt;Xanthomonas campestris&lt;/i&gt; pv. &lt;i&gt;campestris&lt;/i&gt; strain NSTU_AG-1 causing black rot disease isolated from infected cabbage leaves in Bangladesh

Goswami A, Nayem MR, Jhan PK, et al.

<i>Xanthomonas campestris</i> pv. <i>campestris</i> (NSTU_AG-1), the pathogen of black rot disease, was isolated from cabbage in Bangladesh. The genome size was 5,120,760 bp with guanine + cytosine (G + C) content of 64.98% and had …

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Bioinformatics
Full text 2026

Proteomic Profiling Reveals HECTD4-dependent Regulation of Protein Ubiquitination and Signaling Pathways in Prostate Cancer

Takashima Y, Tanaka M, Yoshii K, et al.

<h4>Background/aim</h4>Prostate cancer (PCa) is a leading malignancy in men, and understanding its molecular mechanisms is crucial for advancing therapeutic strategies. Ubiquitination, a key post-translational modification, regulates protein degradation and signaling, playing a vital role in …

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Bioinformatics
Full text 2026

Proteogenomic features define subtypes of mantle cell lymphoma

Yan Y, Chen W, Ge X, et al.

<h4>Abstract</h4>Mantle cell lymphoma (MCL) is a biologically heterogeneous B-cell malignancy. Although genomics and transcriptomics have delineated parts of the MCL disease spectrum, proteomics remains largely unexplored. Here, we conducted a comprehensive proteogenomic analysis integrating genomics, …

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Bioinformatics Transcriptomics
Full text 2026

Towards a Complete DNA Barcode Library of Austrian Lepidoptera

Huemer P, Stark W, Wieser C, et al.

This study presents the first comprehensive molecular assessment of the Lepidoptera fauna of Austria based on DNA barcodes (cytochrome <i>c</i> oxidase I, COI; 658 bp Folmer region). The barcode reference library comprises approximately 23,500 sequences, …

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Bioinformatics