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Full text 2026

Complete genome sequence of a <i>bla</i><sub>OXA-1</sub><i>-</i>carrying <i>Escherichia coli</i> from Laguna Lake, Philippines

Bertuso ALG, Nagpala MJM, De Guzman ACR, et al.

We report the complete genome sequence of <i>Escherichia coli</i> L16-131 (4,850,597 bp chromosome) with five circular plasmids, isolated from Laguna Lake, Philippines. The isolate harbored multiple antimicrobial resistance genes (ARGs); most were computationally predicted to …

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Bioinformatics
Full text 2025

Complete genome sequence of &lt;i&gt;Leeuwenhoekiella parthenopeia&lt;/i&gt; H156, a potential carbohydrate polymer degrader isolated from tidal flat sediment in Zhejiang, China

Zhang W-w, Chen B-x, Su Y, et al.

We report the complete genome sequence of <i>Leeuwenhoekiella parthenopeia</i> H156 isolated from tidal flat sediment in Zhejiang, China. The genome consists of a 4.43 Mbp circular chromosome with annotated 331 carbohydrate-active enzymes. It contains 32.5 …

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Bioinformatics
Full text 2026

Draft genome sequences of &lt;i&gt;Bacillus&lt;/i&gt; and &lt;i&gt;Pseudomonas&lt;/i&gt; species isolated from &lt;i&gt;Cannabis sativa&lt;/i&gt; L. and &lt;i&gt;Chelidonium majus&lt;/i&gt; L

Amaya-Quiroz L, Kaddoura MJ, Rani M, et al.

Draft genome sequences of seven <i>Bacillus</i> strains isolated from <i>Chelidonium majus</i> seeds and six <i>Pseudomonas</i> strains isolated from <i>Cannabis sativa</i> roots and stems are reported. These genome sequences provide a foundation for functional and comparative …

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Bioinformatics
Full text 2026

Synthetic rewriting of the IGH locus

Fu ZH, Ma Y, Cheng S, et al.

V(D)J recombination, which joins V, D, and J genes across immunoglobulin loci, is essential for antibody diversity. To unlock the inherent constraints of V(D)J recombination, we systematically designed, assembled, and shuffled a synthetic human immunoglobulin …

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Bioinformatics
Full text 2026

Complete genome sequence of Zoysia mosaic virus from Japan

Neriya Y, Ringeera KH, Nishigawa H.

We report a complete genome sequence of Zoysia mosaic virus (ZoMV) from Japanese lawngrass. This virus shares around 80% nucleotide identity with the previously reported ZoMV-ZM864 isolate from Manila grass.

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Bioinformatics
Full text 2026

Dissecting genotype-specific effects of disease-associated genetic variants

Farrow SL, Gokuladhas S, Akan IS, et al.

Non-coding variants associated with complex disease can shape gene regulatory networks across multiple genomic loci and cellular contexts. Here, we investigated the functional impact of the Parkinson-disease-associated variant rs11610045 using an isogenic induced pluripotent stem …

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Bioinformatics