Working with the grain: uncovering sorghum quality regulatory networks

Co-expression profiles and protoplast transient overexpression assays are beginning to unravel the complex regulatory network governing sorghum grain quality, revealing key transcription factors (TFs) that control starch and protein biosynthesis, and digestibility (Séne et al., 2026). This integrated approach provides new targets to accelerate improvement of the nutritional value of sorghum through plant breeding and genetic engineering.