The effect of short-term consumption of <i>Bifidobacterium bifidum</i> on the gut microbiome of obese individuals

It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to investigate the effect of a probiotic supplement containing <i>Bifidobacterium bifidum</i> on the intestinal microbiome of people with obesity using high-throughput sequencing on the DNBSEQ-G50 platform. The study demonstrated a positive effect of the supplement on bacterial species such as <i>Bacteroides uniformis</i>, <i>Alistipes putredinis</i>, <i>Alistipes shahii</i>, <i>Dysosmobacter welbionis</i>, and <i>Gemmiger formicilis</i>. Therefore, we suggest the potential use of this bacterial species in the treatment of gut microbiota dysbiosis of obese individuals.