Full text 2026

SEMPLR: an R package for transcription factor binding prediction

Kenney GE, Sherpa RN, Burgess JD, et al.

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Abstract

<h4>Summary</h4>SEMPLR is an R package that predicts transcription factor binding and variant effects using SNP Effect Matrices (SEMs), providing efficient, genome-wide scoring, enrichment testing, and visualization tools for comprehensive analysis of regulatory sequences.<h4>Availability</h4>Available on GitHub at https://github.com/grkenney/SEMPLR and on Bioconductor at https://bioconductor.org/packages/release/bioc/html/SEMPLR.html.