Full text 2026

<i>Salmonella</i> Stanley ST29 carrying IncHI2/ST3-<i>bla</i><sub>NDM-5</sub> plasmid emerged in a 4-month-old infant with diarrhea

Bai Y-M, Gao X-J, Yue C, et al.

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Abstract

<i>Salmonella</i> serovar Stanley ST29 is an emerging foodborne pathogen with community spread potential, while its carbapenem resistance remains uncommon. In a longitudinal pediatric case with diarrhea, two clonal ST29 isolates sampled 2 months apart revealed within-host evolutionary dynamics: Tn<i>7051</i>-mediated excision of <i>bla</i><sub>NDM-5</sub> from an IncHI2/ST3 plasmid. Moreover, phylogenomics connected the case isolate to strains from a healthy carrier and from food-chain-associated sources in the same region (17-18 SNPs), underscoring community dissemination and the need for One-Health surveillance.

Keywords

Infant Plasmid Salmonella Carbapenem-resistant Enterobacterales (Cre)