Full text 2026

Endogenous DNA Damage and Its Role in Human Disease

Bryan EM, Lauderback C.

Bioinformatics

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Abstract

Endogenous DNA damage from metabolism and genome dynamics drives mutation, instability, and disease. New insights from ACS Fall 2025 reveal chemical diversity, metabolic drivers, and repair limits that shape cancer risk and biomarker development.

Keywords

Genomic instability Endogenous Dna Damage Metabolic Dysfunction Dna Repair Pathways Secondary Dna Structures