Full text 2025

Comprehensive genomic insights into <i>Mixta calida</i> isolated from the faecal sample of a tuberculosis patient in India

Pant A, Srinivasan J, Venkadesan S, et al.

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Abstract

<i>Mixta calida</i>, formerly known as <i>Pantoea calida</i>, is a motile Gram-negative, facultatively anaerobic bacterium with coccoid rod morphology. Although previously considered non-pathogenic, emerging case studies indicate its potential role in causing serious infections, including bacteraemia, meningitis, sepsis, and implant-associated infections. This study presents the first whole-genome sequence of <i>M. calida</i> of Indian origin, isolated from the stool sample of a tuberculosis patient undergoing treatment. Sequencing was performed using the Illumina NextSeq 2000 and Oxford Nanopore PromethION platforms. The genomic data provides valuable insights into the antimicrobial resistance traits and mobile genetic elements of the bacterium, contributing to a deeper understanding of its pathogenic potential.

Keywords

Antimicrobial resistance Mobile genetic elements Whole Genome Sequencing Gut Microbiome Mixta Calida