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Whole-genome sequencing of bacterial pathogens can positively impact infectious disease management in clinical contexts, both in individual settings and by assisting infection prevention efforts. However, logistical issues have often prevented its translation into clinical settings. …
Read PDFHLA-G*01:66 differs from HLA-G*01:01:22:01 by one missense nucleotide substitution at position 508 in exon 3.
Read PDFAfrican swine fever is a transboundary disease of wild boar and domestic pigs that is caused by the African swine fever virus (ASFV), with a mortality rate of 100 % in naïve animals. The ongoing …
Read PDF<h4>Background</h4>Granulomatous lobular mastitis (GLM) is a benign, nonspecific inflammatory disease associated with autoimmune dysregulation, pathogenic infection, endocrine disorders, and other etiological factors. Although various treatments for GLM exist, there is currently no standardized approach. <i>Aerococcus …
Read PDFHomatula variegata is a small benthic loach from the upper Yangtze and adjacent basins with aquaculture and ornamental value but no reference genome. We present a near telomere-to-telomere (T2T) chromosome-level assembly built from PacBio HiFi, …
Read PDFHigh-quality reference genomes permit deeper investigation into species' evolution and provide insight into species management and conservation. Next-generation sequencing technologies, such as Oxford Nanopore Technologies, allow researchers to generate high-accuracy long-read genetic data in real-time …
Read PDF<h4>Background</h4>Genetic stability of live-attenuated infectious laryngotracheitis virus (ILTV) vaccines is essential for consistent efficacy and safety; however, marker-based assessments targeting partial genes are often insufficient given the virus's large, structurally complex genome. The ILTV genome …
Read PDFWe report the complete genome sequence of <i>Micrococcus luteus</i> TG3.30, isolated from sugarcane soil in Brazil. The 2.58 Mb genome (GC 72.92%) was assembled from hybrid Illumina-Nanopore sequencing with 99.96% completeness, providing a high-quality resource …
Read PDFHydropotes inermis (Chinese water deer, 2n = 70) is a relatively primitive small Cervidae species naturally distributed along the eastern coast of China and the Korean Peninsula. High-quality genomic resources are essential for investigating its …
Read PDFBACKGROUND: Chromosome-level de novo genome assemblies are vital for many aspects of biological research. Despite technological progress, achieving telomere-to-telomere assemblies remains challenging. Long-read data are critical for a contiguous genome assembly, since repeat regions cannot …
Read PDFWe report draft genome sequences of <i>Ralstonia mannitolilytica</i> strains H3G44 and H3G46 isolated from the gut of captured <i>Tenualosa ilisha</i> in Bangladesh. Oxford Nanopore sequencing generated 4.76 and 4.77 Mb assemblies (66% GC) in three …
Read PDFThe Galápagos Petrel (Pterodroma phaeopygia) is a critically endangered procellariiform seabird endemic to the Galápagos Islands. Once abundant, its populations have sharply declined due to invasive predators, habitat degradation, and destruction of nest burrows. Although …
Read PDFSustainable mangrove fisheries (SMF) is an integrated mangrove fisheries approach used in coastal aquaculture ponds that brings sustainability to coastal aquaculture practices. To track the positive value of mangrove on the aquaculture practices, sediment and …
Read PDFIn this project, we compared whole-genome Borrelia assemblies using reads produced by Oxford Nanopore Technology (ONT) with R9 and R10 chemistry and flow cells to investigate potential improvements between versions. For this, we sequenced two …
Read PDFWe report draft genome sequences of two <i>Streptomyces</i> strains isolated from Atacama Desert soil in Chile. Strains H62 and H72 have genome sizes of 7.9 and 8.0 Mbp with GC contents of 72.4% and 72.3%, …
Read PDFInvasive species are reshaping aquatic ecosystems worldwide at an accelerating pace, with profound ecological and economic impacts. Many crustacean species have demonstrated invasive potential or are already well-established invaders. The green shore crab, Carcinus maenas, …
Read PDFSea buckthorn (<i>Hippophae rhamnoides</i> L.) is a valuable plant whose fruits are rich in biologically active compounds. We sequenced the genome of variety Triumf of <i>H. rhamnoides</i> ssp. <i>mongolica</i> Rousi on the Oxford Nanopore Technologies …
Read PDF<h4>Background</h4>Altered circulating cell-free DNA (cfDNA) fragmentation patterns serve as cancer biomarkers, yet standard short-read sequencing fails to capture the full fragment-length spectrum. Although cancer patients often exhibit elevated cfDNA, the relationship between high cfDNA concentration …
Read PDFGlucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzymopathy and poses a major concern on safe administration of oxidative drugs, including antimalarials such as primaquine and tafenoquine. Common diagnostic approaches, such as enzyme assays, …
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