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Pseudomonas species are globally distributed bacteria that influence soil and plant health, functioning as both pathogens and plant growth-promoting rhizobacteria (PGPR). Genomic analyses have revealed the genetic basis for their ecological versatility, including the evolution …
Read PDFThe bovine respiratory disease (BRD) complex is a major health and welfare challenge in the cattle industry worldwide, with substantial economic and antimicrobial resistance implications. <i>Pasteurella multocida</i> (PM) is a key bacterial agent of BRD; …
Read PDFDespite drastic advances in psychiatric genetics, comparatively little attention has focused on the translation of those discoveries into real-world impact. This paper reviews the processes and considerations for integrating new techniques into clinical practice and …
Read PDFThe polychaete Capitella teleta is a primary model for evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology. Although it was the first polychaete genome sequenced, the original assembly is outdated by modern standards. Here, we …
Read PDFThe necrotrophic predatory yeast Saccharomycopsis schoenii preys on diverse fungal species including multidrug-resistant Candida auris, making it a promising candidate for fungal biocontrol. Despite growing interest in its predation mechanisms, a high-quality reference genome is …
Read PDFBACKGROUND: Currently, the American College of Medical Genetics and Genomics (ACMG) carrier screening (CS) guidelines do not recommend routinely screening for conditions with carrier frequencies ≤ 1:200. Advances in DNA sequencing and declining costs, alongside …
Read PDFGlobal climate change exerts a far-reaching influence on the geographical distribution, phenological patterns, and genetic diversity of plants, presenting a grave challenge to the survival and evolution of species. Owing to its robust ecological adaptability, …
Read PDFThe human complement of chromosomes differs from our closest primate relatives by virtue of a unique chromosome fusion event. In this issue of Cell Genomics, Yang et al. provide the first detailed analysis of the …
Read PDFGroE is a chaperonin folding system consisting of GroEL (Cpn60, a 60 kDa chaperonin), and the smaller co-chaperonin GroES (Cpn10). Many 'client' proteins require GroE to fold properly, including several that are essential for cell …
Read PDFThe underrepresentation of Brazil and other Latin American nations in global genomic research is a consequence of multifaceted challenges. Persistent underfunding and infrastructure limitations have hampered the development and implementation of large-scale genomic studies in …
Read PDF<i>Colletotrichum camelliae</i> Massee, a member of <i>Colletotrichum gloeosporioides</i> species complex (CGSC), is an economically important fungal pathogen that causes significant damage to <i>Camellia sinensis</i> (tea) and other C<i>amellia</i> species that include ornamental crops. Although the …
Read PDFRHEBL1 (RHEB2), a member of the Ras superfamily, has established roles in tumor-promoting signaling pathways including mTOR activation and NF-κB transcription; however, its specific role in oral squamous cell carcinoma (OSCC) and its regulation by …
Read PDF<h4>Purpose</h4>Assess US registered nurse genomic competency.<h4>Design</h4>Administered the Genetics and Genomics Nursing Practice Survey (GGNPS).<h4>Methods</h4>GGNPS assesses genomic knowledge, skills, attitudes, confidence, and utilization in nursing practice. Distributed by the American Nurses Association via email and online …
Read PDFEpigenome-wide association studies (EWAS) has become an indispensable approach for elucidating the epigenetic basis of complex traits. EWAS Open Platform (https://ngdc.cncb.ac.cn/ewas/) includes three main components: EWAS Atlas (curated associations from publications), EWAS Data Hub (normalized …
Read PDFHere we report the genome sequence of the ascomycete pathogenic fungus <i>Colletotrichum acutatum</i> isolate #83 obtained from the rootstock of strawberries in Santa Maria, CA.
Read PDF<h4>Background</h4>Klebsiella pneumoniae is a major opportunistic pathogen and a recognized contributor to the global burden of antimicrobial resistance (AMR). Although traditionally associated with healthcare settings, it is increasingly detected in environmental compartments influenced by anthropogenic …
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