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10021 results

Full text 2026

Short-chain fructo-oligosaccharides modulate gut microbiota composition and metabolism: dose-response assessment in an <i>ex vivo</i> gut model

Bressuire C, Thirion F, Chiaravano L, et al.

Short-chain fructo-oligosaccharides (scFOS) are prebiotic fiber rapidly fermented in the colon and known to stimulate beneficial bacteria, such as <i>Bifidobacterium</i> spp. and <i>Lactobacillaceae</i>. While their overall effects on the gut microbiota are established, the dose-response …

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Metagenomics
Full text 2025

Coupling culturomics and metagenomics sequencing to characterize the gut microbiome of patients with cancer treated with immune checkpoint inhibitors

Diop K, Mbaye B, Nili S, et al.

<h4>Background</h4>The gut microbiome represents a novel biomarker for melanoma and non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICI). Gut microbiome metagenomics profiling studies of patients treated with immunotherapy identified bacteria associated …

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Metagenomics
Full text 2025

Real-time analysis and visualization of nanopore metagenomic samples with MARTi

Peel N, Martin S, Heavens D, et al.

The emergence of nanopore sequencing technology has the potential to transform metagenomics by offering low-cost, portable, and long-read sequencing capabilities. Furthermore, these platforms enable real-time data generation, which could significantly reduce the time from sample …

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Bioinformatics Metagenomics Nanopore Sequencing
Full text 2026

The Gut-Brain Axis as a Mediator of Environmental Endocrine Disruptors in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Mechanistic Synthesis

Wu H, Yu M, Huang S, et al.

The rising global prevalence of attention-deficit/hyperactivity disorder (ADHD) underscores the importance of environmental factors, particularly environmental endocrine-disrupting chemicals (EEDs), whose mechanistic links to ADHD remain unclear. The gut-brain axis, a key modulator of neurodevelopment, is …

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Metagenomics
Full text 2025

Investigating microbial population structure and function in the chicken caeca and large intestine over time using metagenomics

Star-Shirko B, Pangga GM, McKenna A, et al.

<h4>Objectives</h4>Although taxonomic variations in chicken gut microbiota have been previously documented, their functional capacity remain poorly understood. To gain a better understanding, we incorporated whole genome shotgun metagenomics to analyse microbial communities of two different …

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Metagenomics
Full text 2026

Urban forest restoration enhances soil microbial functional potential and functional insurance via shifts in β-diversity

Brachmann S, Kiesewetter KN, Liddicoat C, et al.

<h4>Background</h4>Forest restoration has primarily been evaluated through changes in aboveground communities, while belowground microbial communities-critical drivers of ecosystem functions-remain less understood. Moreover, studies of soil microbes have focused largely on community structure, which does not …

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Metagenomics