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<b>Background.</b> <i>Mycoplasma pneumoniae</i> (<i>MP</i>) is a common causative pathogen of community-acquired pneumonia in children, with clinical presentations ranging in severity. Early stratification and timely intervention are essential for improving patient outcomes. However, a major clinical …
Read PDFThe relationship between domestic cats and humans may facilitate transmission of viruses between the two hosts. Metagenomic analyses of 70 urban feline swab samples identified six high-quality draft genomes from felid alphaherpesvirus 1 and feline …
Read PDFStress-induced dysbiosis exacerbates mental health by modulating the nervous system and gut permeability. In this study, we investigate the therapeutic potential of porous silicon water-mixed catechin in alleviating chronic stress-induced dementia in rats. In a …
Read PDFDeep-sea ecosystems remain poorly understood due to exploration challenges. Despite the advancements metagenomics have brought to the understanding of the ocean microbiome, the diversity of marine viruses, particularly in the deep sea, is still not …
Read PDFAncient DNA (aDNA) research has revolutionised archaeology and forensic science by enabling genomic recovery from highly degraded remains. This review explores the biochemical and environmental factors influencing aDNA preservation, alongside methodological advances that have improved …
Read PDF<h4>Background</h4>Some people with multiple sclerosis display changes in their gut microbiota with separate evidence suggesting that symptoms may worsen following a high-fibre diet. We hypothesised that in people with multiple sclerosis whose gut microbiota are …
Read PDFThis study aimed to assess the anti-hyperuricemia efficacy of Zhejiang psyllium polysaccharides (ZPP) in rats and to explore its underlying mechanism. Hyperuricemia was induced by intragastric administration of potassium oxonate, hypoxanthine, and adenine. The serum …
Read PDFPrasinoviruses infect some of the most abundant photosynthetic eukaryotes in the ocean, shaping microbial dynamics and playing a major role in nutrient cycling. Despite their ecological significance, they have only been explored in a few …
Read PDFThe gut microbiota is recognized as a programmable metabolic organ that governs systemic homeostasis. Recent advances (2023-2025) have pivoted Type 2 Diabetes Mellitus (T2DM) research from a host-centric perspective toward a failure of bidirectional host-microbe …
Read PDFWetland ecosystems provide interfaces for the transmission of microbial pathogens and antimicrobial resistances (AMR) between migratory birds, wild and domestic animals, and human populations. The efficient surveillance of wetlands is, however, challenging, since the typically …
Read PDFBisphenol A (BPA) is a persistent environmental contaminant requiring effective removal strategies. Biofilms offer advantages over conventional activated sludge for refractory compound degradation, yet the specific microorganisms and mechanisms driving BPA removal in biofilms remain …
Read PDFMetagenomics holds promise as a comprehensive, nontargeted tool for environmental monitoring. However, one key limitation is that the quantitative capacity of metagenomics is not well-defined. Here, we demonstrated a quantitative metagenomic technique and benchmarked the …
Read PDFBACKGROUND: The human microbiome plays an emerging role in cancer biology, yet its contribution to endometrial cancer (EC) remains poorly defined. This study investigates the microbial composition of the vaginal, rectal, and endometrial sites in …
Read PDFHuman reads are a key contaminant in microbial metagenomics and enrichment-based studies, requiring removal for computational efficiency, biological analysis, and privacy protection. Various in silico methods exist, but their effectiveness depends on the parameters and …
Read PDFNon-typhoidal <i>Salmonella</i> (NTS) and thermotolerant <i>Campylobacter</i> remain leading causes of bacterial gastroenteritis worldwide, with a disproportionate burden in low- and middle-income regions. This updated review synthesizes current evidence on their epidemiology, antimicrobial resistance (AMR) dynamics, …
Read PDF<h4>Background</h4>Microbial communities in mining environments exhibit unique metabolic adaptations to extreme conditions, such as high metal concentrations and low pH. Their relatively low species complexity makes them an attractive model for fine-scale evolutionary analysis; nonetheless, …
Read PDFFour new variants of Orsay virus were identified from wild isolates of <i>Caenorhabditis elegans</i> nematodes collected from decaying plant matter in France. Near-complete genomes of the viruses were determined by metagenomic sequencing. The four genomes …
Read PDFMicrobial biodegradation represents a promising approach to addressing global plastic pollution, yet the metabolic pathways and environmental origins of polymer-degrading microorganisms remain incompletely characterized. This review synthesizes current knowledge on biodegradation mechanisms across major polymer …
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