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Understanding the relative influence of immigration and species sorting in wastewater treatment systems is essential, as bacteria in influent wastewater can significantly impact treatment system functionality. This study investigated the contribution of immigration to the …
Read PDFDiabetes mellitus is a leading metabolic and non-communicable disease, affecting nearly 537 million adults worldwide. Recent research highlights the gut microbiota as a crucial factor in the onset and progression of diabetes. Gut microbial dysbiosis, …
Read PDF<h4>Introduction</h4>Dryland ecosystems are increasingly exposed to extreme heat and prolonged water limitation. Facultative crassulacean acid metabolism (CAM) enables certain desert plants to enhance water-use efficiency and adjust carbon assimilation under stress conditions. <i>Mesembryanthemum forsskalii</i> Hochst. …
Read PDFAntimicrobial resistance (AMR) is one of the most urgent health threats of the 21st century. Surveillance is needed to enable timely interventions, close knowledge gaps, and anticipate long-term trends. Current frameworks rely heavily on clinical …
Read PDFThe crisis of antimicrobial resistance (AMR) is escalating while the antibiotic pipeline remains stagnant. Our bibliometric analysis of eight decades of literature reveals a critical imbalance: research on AMR has grown, yet fundamental research on …
Read PDFThe microbiome is a key regulator of host homeostasis and immune activity, in part through the production of metabolites. These microbiota-derived metabolites can modulate both the innate and adaptive immune system, as well as directly …
Read PDFAntibiotic resistance continues to erode the effectiveness of modern medicine, creating an urgent demand for rapid and reliable diagnostic solutions. Conventional diagnostic approaches, including culture-based susceptibility testing, remain the clinical reference standard but are constrained …
Read PDFMicro and nano-plastics pose a significant threat to the global environment, affecting agricultural systems, food security, and human health. Some studies indicate that microplastics can induce physiological damage in plants, including oxidative stress, reduced germination, …
Read PDF<b>Background</b>: Periodontitis is a chronic inflammatory disease mostly associated with <i>Porphyromonas gingivalis</i> infection and characterized by progressive destruction of the supporting structures of the tooth, including the gingiva, periodontal ligament and alveolar bone. However, the …
Read PDFStandard protocols for meta-analysis of association studies are inadequate for microbiome data due to their complex compositional structure, leading to inaccurate and unstable microbial signature selection. To address this issue, we introduce Melody, a framework …
Read PDFEfficient DNA extraction from coastal sediments is a critical step for studying microbial communities, especially when targeting high-molecular-weight DNA for long-read sequencing. Here, we compare a cost-effective laboratory-made (LM) extraction method with two widely used …
Read PDF<h4>Background</h4>Influenza A viruses (IAVs) are significant pathogens with complex transmission dynamics in aquatic ecosystems, yet their persistence, evolutionary relationships, and associations with environmental microorganisms remain poorly understood. This study aimed to elucidate the phylogenetic characteristics …
Read PDF<b>Background:</b> Steamed <i>Panax notoginseng</i> saponins (SPNSs) can alleviate cyclophosphamide-induced anemia. However, the hepatointestinal effects of SPNSs and their role in ameliorating cyclophosphamide-induced anemia remain unexplored. <b>Objective:</b> To elucidate the hepatointestinal effects of SPNSs and their …
Read PDFDue to its high digestibility, rich nutrient profile, and potential probiotic content, goat milk is an essential nutritional resource, particularly for individuals with cow milk allergies. This review summarises the current state of microbial diversity …
Read PDF<h4>Introduction</h4>Liver failure is a severe condition marked by circulatory failure, systemic inflammation, and gut microbial dysbiosis. This dysbiosis worsens liver damage by reducing beneficial metabolites and increasing harmful products. This study investigates the effects of …
Read PDFSoil microorganisms are fundamental to soil sustainability, governing organic matter turnover, nutrient cycling, soil structure formation, and plant health regulation. In the context of accelerating soil degradation, climate change, and expanding agricultural salinization, understanding how …
Read PDFCirculating microbiome-related metabolites have emerged as promising biomarkers for coronary heart disease. A recent multi-stage study in PLOS Medicine strengthens signal prioritization but highlights the persistent gap between association and causality.
Read PDFHepatic alveolar echinococcosis (HAE), a life-threatening zoonosis, poses formidable surgical challenges when involving critical vasculature. Herein, we reported the periprocedural management dilemmas in radical resection for advanced HAE. A 58-year-old female visited the outpatient department …
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