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The deep sea remains a major reservoir of underexplored microbial diversity and biosynthetic novelty. Here, we describe three bacterial species isolated from Atlantic sponges, including <i>Stappia quadratibracata</i> sp. nov., <i>Bacillus crepusculi</i> sp. nov., and <i>Psychrobacter …
Read PDF<h4>Background</h4>Rare actinomycetes, particularly Gordoni spp., are emerging as critical sources of bioactive metabolites and opportunistic pathogens.<h4>Results</h4>In this study, we isolated three novel Gordonia strains from soil samples and characterized their taxonomic status using a polyphasic …
Read PDFMyxobacteria are Gram-negative, spore-forming predatory bacteria isolated from diverse environmental samples that feed on other microbes for their survival and growth. However, no reports of cultured representatives from the human gut have been published to …
Read PDFThe taxonomy of Burkholderia sensu lato (s.l.) has been revisited using genome-based tools, which have helped differentiate closely related species. Many species from this group are indistinguishable through phenotypic traits and 16S rRNA gene sequence …
Read PDFGiant viruses (GVs) play crucial roles in the global ocean microbial food web and biogeochemistry. Recent metagenomic advances have uncovered >1800 new GV genomes from the world's oceans. While this rapid increase in genomic information …
Read PDFHeavy metal resistance represents a critical microbial trait shaped by lineage-specific evolutionary pressures, yet its genomic foundations and diversification across major bacterial taxa remain poorly resolved. This study presented a comparative pangenomic analysis of <i>Aeromonas</i> …
Read PDFA Gram-positive, facultatively anaerobic, rod-shaped actinomycete bacterium, strain NTE-D12<sup>T</sup> was isolated from the filtrate (< 0.22 μm pore size) of an electrochemical enrichment culture. The strain grew in R2A medium at 15-40 °C (optimum 30 …
Read PDFA novel Gram-stain-positive, black-pigmented bacterium, designated as WL48A <sup>T</sup>, was isolated from the surface of badland sedimentary rock in the Red Desert of Wyoming and characterized using a polyphasic taxonomic approach. Good growth occurred at …
Read PDFPreterm infants born <32 weeks gestation have abnormal microbial colonisation and dysregulated inflammation within the gut. Preterm infant-derived intestinal organoids (PIOs) represent a valuable model for investigating gut microbiome-host interactions and inflammatory responses. We optimised …
Read PDFChildhood illnesses from infectious diseases in low- and middle-income countries contribute substantially to the global under-five mortality. Many hospitalized children experience incomplete recovery, readmission, and post-discharge mortality despite guideline-directed care. However, targeted interventions remain elusive …
Read PDFThe increasing global burden of antimicrobial resistance (AMR) has been identified as a critical public health crisis, necessitating the development of robust, real-time surveillance frameworks to evaluate AMR dynamics. Sewage surveillance is emerging as a …
Read PDFIdentifying the genetic relatedness of resistant bacterial pathogens in healthcare settings can help identify undetected transmission events and outbreaks. However, current methods are time- and resource-intensive. We evaluated a rapid neighbor typing method paired with …
Read PDFMicrobes are omnipresent, thriving in a range of habitats, from oceans to soils, and even within our gastrointestinal tracts. They play a vital role in maintaining ecological equilibrium and promoting the health of their hosts. …
Read PDFGut bacteriophages profoundly impact microbial ecology and health<sup>1-3</sup>; yet, they are understudied. Using deep long-read bulk metagenomic sequencing, we tracked prophage integration dynamics in stool samples from six healthy individuals, spanning a 2-year timescale. Although …
Read PDFFreshwater ecosystems are under increasing pressure from pollution, habitat degradation and climate change, highlighting the need for reliable biomonitoring approaches to assess ecosystem health and identify the causes of biodiversity and ecosystem service loss. Characterisation …
Read PDFSmoking has been associated with increased risk of periodontitis. The aim of the present study was to compare the periodontal disease severity among smokers and nonsmokers which may help in better understanding of predisposition to …
Read PDFThe expansion of intensive poultry farming has led to a substantial increase in antibiotic use, which, in turn, has promoted the accumulation of antibiotic resistance genes (ARGs). The chicken gut serves as a reservoir for …
Read PDF<h4>Background</h4>Ctenocephalides felis is a common ectoparasite of dogs and cats and can transmit a variety of pathogens including Bartonella and Rickettsia species. These bacteria, along with the known endosymbiont Wolbachia, are well-documented members of the …
Read PDFBacterial pathogens adapt rapidly to clinical and within-host selective pressures<sup>1</sup>. Insertion sequences (IS) are transposable elements that can contribute to pathogenic adaptation<sup>2</sup>, but their activity and consequences in contemporary clinical populations are not well characterized. …
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