Search the literature by keyword, topic, or author. Filter to articles with full text available.
1201 results
Iron-oxidizing Betaproteobacteria and Zetaproteobacteria are generally associated with freshwater and marine environments, respectively. Despite repeated cross-environment observations of these taxa, there has been no focused exploration of the genomes of marine <i>Gallionella</i> (Betaproteobacteria) to understand …
Read PDFThe bacterial order Pelagibacterales (SAR11) is widely distributed across the global surface ocean, where its activities are integral to the marine carbon cycle. High-quality genomes from isolates that can be propagated and phenotyped are needed …
Read PDFThe evolutionary origins and taxonomic framework of giant viruses related to the family <i>Mamonoviridae</i> and its relative group, including clandestinovirus, remain unclassified due to gaps in genome size and host range between these two groups. …
Read PDFOxygenic photosynthesis, which converts solar energy into carbohydrates via a linear electron transport chain and two photosystems (PSII and PSI), first appeared in cyanobacteria approximately 3.3 Ga and drove the Great Oxidation Event around 2.4 …
Read PDF<h4>Introduction</h4>Crude oil-contaminated soils harbor bacteria with specialized hydrocarbon-degrading capabilities, yet the <i>Stenotrophomonas</i> genus remains incompletely characterized at the species level. Strain ASS1, a motile Gram-negative rod, was isolated from crude oil-contaminated soil in Tabasco, Mexico, …
Read PDFVertical transmission of marine particles brings ocean surface cyanobacteria into the deep ocean, where heterotrophic cyanobacterial lineages probably evolve to adapt to new environments even in oxygen-depleted zones. At present, active cyanobacteria have rarely been …
Read PDFThe human oral microbiome, a complex ecosystem of niche-specific communities influenced by local ecological factors, plays a critical role in health and disease. <i>Capnocytophaga</i> species are prevalent in the human mouth, often abundant in dental …
Read PDFMembers of the bacterial family <i>Endozoicomonadaceae</i> are ubiquitous marine symbionts associated with diverse hosts, including corals, sponges, molluscs, and fishes. Despite their ecological pervasiveness, inhabiting hosts in deep-sea vents and sunlit coral reefs, their taxonomy …
Read PDFPhylogenetic marker genes are traditionally selected from a fixed collection of whole genomes representing major microbial phyla, covering only a small fraction of gene families. However, most microbial diversity resides in metagenome-assembled genomes, which exhibit …
Read PDFCardiovascular diseases (CVDs) rank among the most prevalent conditions globally, encompassing coronary heart disease, hypertension, cardiomyopathy, and heart failure. The global prevalence of CVD continues to rise despite available therapies such as interventional procedures and …
Read PDF<h4>Background</h4>Asthma is a Th2-skewed inflammatory disorder characterized by eosinophilic infiltration, cytokine dysregulation, and airway remodeling. Emerging evidence highlights the role of immunometabolic pathways and the gut-lung axis in asthma pathogenesis.<h4>Methods</h4>We investigate the therapeutic effects of …
Read PDFSoutheast Asia (SEA) faces persistent gaps in regional understanding and control of ticks and tick-borne diseases (TBDs) despite recent advances (2023-2025). The second international symposium on ticks and TBDs in SEA (Singapore, August 2025), following …
Read PDF<h4>Background</h4><i>Staphylococcus aureus</i> (SA) remains a global health threat due to its increasing drug resistance and intracellular persistence, which compromise the conventional antibiotic efficacy. Host-directed therapy (HDT) has emerged as a promising alternative by modulating host …
Read PDFPhotoaffinity-based chemoproteomics provides a strategy for interrogating protein engagement and networks within complex biological systems. In the context of carbohydrate metabolism, however, linking the probe structure to glycan-processing networks remains challenging due to the diversity …
Read PDFInterindividual variability in drug pharmacokinetics and susceptibility to drug-drug interactions remain major barriers in precision dosing, particularly for narrow therapeutic index drugs. While genetic factors contribute, much variability arises from dynamic influences such as physiology, …
Read PDFLong-read sequencing offers the potential to improve metagenome assemblies and provide more robust assessments of microbial community composition and function than short-read sequencing. We applied Pacific Biosciences (PacBio) CCS (circular consensus sequencing) HiFi shotgun sequencing …
Read PDF<h4>Background</h4>Metagenomic data can be used to profile high-importance genes within microbiomes. However, current metagenomic workflows produce data that suffer from low sensitivity and an inability to accurately reconstruct partial or full genomes, particularly those in …
Read PDFObtaining complete and accurate bacterial genomes is vital for studying the characteristics of uncultured bacteria. Single-cell genomics is a promising approach for the culture-independent recovery of bacterial genomes from individual cells. However, single-amplified genomes (SAGs) …
Read PDFDNA methylation plays a crucial role in the survival of bacteriophages (phages), yet the understanding of their genome methylation remains limited. In this study, DNA methylation patterns are analyzed in 8848 metagenome-assembled high-quality phages from …
Read PDFThe microbiome is a complex community of microorganisms, encompassing prokaryotic (bacterial and archaeal), eukaryotic, and viral entities. This microbial ensemble plays a pivotal role in influencing the health and productivity of diverse ecosystems while shaping …
Read PDF