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<h4>Background</h4>Disruptions in the early-life gut microbiome have been reported to be associated with various health conditions. However, few studies have investigated the establishment of the gut microbiota in the immediate postnatal period.<h4>Aim</h4>To characterize the gut …
Read PDF<i>Bacillus cereus</i> HS120 was isolated from the stomach of a healthy hilsa (<i>Tenualosa ilisha</i>) in Nabogonga River, Bangladesh. Here, we present a 5,673,590-bp draft genome with 35.23 % GC content, which encodes numerous biosynthetic gene …
Read PDFMeningiomas are prevalent intracranial tumors with poorly understood extraneural drivers. While the gut-brain axis influences neuro-oncogenesis, meningioma-specific gut microbiome alterations and their clinical implications remain uncharacterized. This study integrated 16S rRNA sequencing of fecal samples …
Read PDFMolecular methods in clinical and research applications frequently encounter complex mixtures of human and microbial DNA, sometimes alongside environmental or reagent contaminants. In metagenomic studies, the presence of host contamination poses a significant challenge, reducing …
Read PDF<b>The aim of the study</b> was to estimate the efficiency of identifying bacterial agents in native cardiac valves affected by infective endocarditis using 16S rRNA metabarcoding.<h4>Materials and methods</h4>The study material involved 20 native cardiac valve …
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Read PDF<h4>Background</h4>While evidence linking the gut microbiome (GM) to cancer immunotherapy is growing, data regarding its role in chemotherapy remains limited. This study aims to investigate the effect of chemotherapy on GM composition and its potential …
Read PDFBACKGROUND: Group A streptococcus (GAS) could lead to various disease types in children, but central nervous system (CNS) infections are uncommon. In this paper, we analyzed the clinical features of a GAS case with meningitis …
Read PDF<h4>Background</h4>Phosphorus (P) utilization is a complex trait influenced by numerous genetic variants. The jejunum is the primary site of P absorption in poultry. Therefore, identifying the genetics that regulate transcription in jejunum may help uncover …
Read PDF<h4>Background</h4>Norovirus is a leading cause of acute gastroenteritis and spreads efficiently in closed, mobile cohorts such as organized travel groups. This case is notable for the real-time detection and genomic confirmation of a cross-border outbreak …
Read PDFLarge language models (LLMs) are evolving from passive predictors into agentic systems capable of planning, tool-use, and multimodal reasoning. This shift is especially consequential for biology, where complex, noisy, and multi-scale data require adaptive and …
Read PDF<h4>Motivation</h4>Longitudinal microbiome studies (LMS) are increasingly common but have analytic challenges including nonindependent data requiring mixed-effects models. Furthermore, large amounts of data motivate exploratory analysis to identify factors related to outcome variables. Although change analysis …
Read PDFModern crop varieties may exert reduced influence on their microbiome compared to their progenitors, as plant-microbe interactions were not targeted during breeding. Moreover, formerly beneficial microbiome functions might no longer be relevant in modern agricultural …
Read PDFDespite widespread vaccination, pertussis resurgence persists due to waning immunity and emerging resistant strains in <i>Bordetella pertussis</i>. This study employs a pangenomics-driven reverse vaccinology approach to identify novel vaccine candidates. Analyzing 160 genomes revealed a …
Read PDFStenotrophomonas spp. are increasingly recognized as opportunistic pathogens with high levels of antimicrobial resistance (AMR). Despite their clinical importance, genomic diversity within the genus remains underexplored, particularly in Thailand and Southeast Asia. Ten Stenotrophomonas strains …
Read PDFGMrepo (Gut Microbiome Data Repository) is a curated and consistently annotated database of human gut metagenomes, designed to improve data reusability and enable cross-project and cross-disease comparisons. In this latest release, GMrepo v3 has been …
Read PDFThe effects of genotypes (HD3086 and PBW343) and soil physicochemical properties on the wheat rhizospheric bacterial communities along the trans Indo-Gangetic plains were studied. The trans-Indo-Gangetic Plains of India are one of the areas in …
Read PDF<h4>Background</h4>With growing attention to environmental impacts, the dairy sector is increasingly focused on implementing strategies that lower methane emissions and enhance sustainability while maintaining productivity and economic viability. Utilizing agro-industrial by-products as alternative feed ingredients …
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