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Coral reefs are biodiversity hotspots increasingly threatened by climate-induced bleaching, yet profiling the coral holobiont-the host and its associated microbiota-remains technically challenging due to high host-DNA contamination (often >95%) and the lack of comprehensive reference …
Read PDFThe gut microbiota has emerged as a key factor in the pathophysiology of inflammatory bowel disease (IBD), providing novel opportunities for diagnostic innovation. Traditional biomarkers, such as C-reactive protein and fecal calprotectin, are widely used …
Read PDFThe gut microbiome is defined as the collective assembly of microbial communities inhabiting the gut, along with their genes and metabolic products. The gut microbiome systematically regulates host metabolism, immunity, and neuroendocrine homeostasis via interspecies …
Read PDF[This corrects the article DOI: 10.1371/journal.pone.0323382.].
Read PDF<b>Background</b>: Acute high-intensity noise exposure represents a critical environmental stressor; however, its impact on brain function and the underlying mechanisms remain incompletely understood. This study aimed to investigate the effects of acute high-intensity noise exposure …
Read PDFTo meet the rising food demands of our growing population, the Food and Agriculture Organization proposed edible insects as sustainable sources of animal protein. Although hundreds of million people already consume insects around the tropics, …
Read PDF<i>Daqu</i>, a representative solid-state fermentation product, produces saccharifying enzymes to degrade sorghum starch into fermentable sugars for ethanol synthesis. Spatial heterogeneity in <i>Daqu</i> drives community assembly. However, its regulatory role in enzyme-driven saccharification remains unclear. …
Read PDFThe current research was conducted to evaluate the impact of various crude protein (CP) concentrations in diets on growth performance, nutrient digestibility, nitrogen deposition, rumen fermentation, microbial community, and serum metabolomics in growing goats. Fifty …
Read PDFPlasma cell-free RNA (cfRNA) metagenomics is increasingly explored for blood-based pathogen detection, but the structure of the shared background "blood microbiome", the reproducibility of reported signals, and the practical limits of this approach remain unclear. …
Read PDFLignocellulose is a promising renewable resource for anaerobic biochemical production, but its microbial conversion remains challenging. To elucidate metabolic networks in lignocellulose-degrading consortia, inocula of various origins were enriched on cellulose or xylan. Community composition …
Read PDFSoil microbial communities respond quickly to natural and/or anthropic-induced changes in environmental conditions. Metagenomics allows studying taxa that are often overlooked in microbiota studies, such as protists or viruses. Here, we employed metagenomics to characterise …
Read PDFA draft metagenome-assembled genome was recovered from an anaerobic consortium capable of complete reductive dechlorination of trichloroethene to ethene. The draft genome, assigned to a <i>Dehalogenimonas</i> species, is 1.84 Mb in size with a G …
Read PDF<h4>Background</h4>Emerging evidence implicates the gut microbiota in the pathogenesis of adenomyosis (AM); however, whether this association is causal and through which mechanisms it operates remain largely unknown.<h4>Methods</h4>To interrogate potential causal relationships, we performed a two-sample …
Read PDFDiet may influence the gut microbiota and subsequently affect the host's health. Recent developments in methods analyzing the composition and function of the gut microbiota allow a deeper understanding of diet-gut microbiota relationships. A state-of-the-art …
Read PDFThe gut microbiota, a highly individualized microbial community, is increasingly recognized for its role in weight regulation and metabolic health. This narrative review examines the bidirectional associations between gut microbiota and weight management, focusing on …
Read PDFGut microbiota dysbiosis is implicated in metabolic disorders, yet taxonomic and functional alterations in canine diabetes remain incompletely defined. Here, we performed shotgun metagenomic sequencing of fecal samples from 38 diabetic dogs and 37 healthy …
Read PDFBACKGROUND: Bartonella quintana is a recognized cause of blood culture-negative endocarditis, often associated with predisposing social factors or pre-existing valvulopathy. Diagnosis is challenging and relies on advanced microbiological techniques. CASE PRESENTATION: A 17-year-old Tibetan herdsman …
Read PDFThe interplay between diet and gut microbiome composition is complex. Faecal metabolites, the end products of human and microbial metabolism, provide insights into these interactions. Here, we integrate faecal metabolomics, metagenomics, and habitual dietary data …
Read PDFPractical laboratory of the most functional metagenomics courses focuses on activities aimed at providing specific skills in bioinformatics through the analysis of genomic datasets. However, sequence-based analyses of metagenomes should be complemented by function-based analyses, …
Read PDF<b>Background</b>: Mangrove ecosystems are critical coastal environments providing ecological services and acting as buffers between terrestrial and marine systems. Rising antibiotic use in aquaculture and coastal agriculture has led to the dissemination of antibiotic-resistant bacteria …
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