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307 results

Full text 2026

Pangenome analysis of nine soybean cyst nematode genomes reveals hidden variation contributing to diversity and adaptation

Santos LBD, Showmaker KC, Masonbrink RE, et al.

<h4>Background</h4>The soybean cyst nematode (SCN) is a persistent threat to soybean production. SCN populations continually overcome resistant cultivars, causing significant yield losses. Studies conducted with a single reference genome restrict our understanding of intraspecific diversity, …

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Structural Variants
Full text 2025

Chromosome-level genome assembly and annotation of Chinese herring (Ilisha elongata)

Liu B, Niu X, Zhang C, et al.

The Chinese herring (Ilisha elongata) is a commercially and scientifically significant fish species. In this study, we conducted high-precision whole-genome sequencing using two high-throughput platforms: second-generation MGI and third-generation PacBio. Hi-C technology assisted in assembling …

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Genome Assembly Structural Variants
Full text 2025

Genome-Wide Inference of Essential Genes in &lt;i&gt;Dirofilaria immitis&lt;/i&gt; Using Machine Learning

Campos TL, Korhonen PK, Young ND, et al.

The filarioid nematode <i>Dirofilaria immitis</i> is the causative agent of heartworm disease, a major parasitic infection of canids, felids and occasionally humans. Current prevention relies on macrocyclic lactone-based chemoprophylaxis, but the emergence of drug resistance …

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Nanopore Sequencing Structural Variants Transcriptomics
Full text 2025

Creating a consensus genome assembly of &lt;i&gt;Myxococcus xanthus&lt;/i&gt; DZ2 by resolving discrepancies between two complete genomes of the same strain and uncovering the Mx-alpha prophage region diversity across phylum Myxococcota

Mahanta U, Sharma G.

<i>Myxococcus xanthus</i> DZ2, a model myxobacterium, has three reported genome assemblies, including two recent complete assemblies (MxDZ2_Tam and MxDZ2_Nan) from the same culture stock. These assemblies misreported their circular nature and differed by 6.4 kb, …

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Genome Assembly Structural Variants
Full text 2026

Independent centromeric expansions define giant hornet genomes

Ontano A, Sim SB, Jenkins J, et al.

BACKGROUND: The Vespa lineage of hornets demonstrate the potential to displace native species and cause significant damage to US apiculture through predation. In spite of introductions in recent years to North America, eradication efforts have …

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Nanopore Sequencing Structural Variants
Full text 2025

The haplotype-resolved assembly of COL40 a cassava (Manihot esculenta) line with broad-spectrum resistance against viruses causing Cassava brown streak disease unveils a region of highly repeated elements on chromosome 12

Thoben C, Pucker B, Winter S, et al.

Cassava (Manihot esculenta Grantz) is a vital staple crop for millions of people, particularly in Sub-Saharan Africa, where it is a primary source of food and income. However, cassava production is threatened by several viral …

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Genome Assembly Structural Variants
Full text 2025

Beyond single references: pangenome graphs and the future of genomic medicine

Nyaga DM, Zaied RE, Silander OK, et al.

Genomic medicine relies on single reference genomes that miss crucial genetic diversity, creating diagnostic gaps that disproportionately affect underrepresented populations. Pangenome graphs, collections of diverse genomes represented as interconnected genetic paths, offer a powerful alternative …

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Genome Assembly Nanopore Sequencing Structural Variants