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3689 results

Full text 2026

A sorghum-anchored pan-grass syntenic gene set in grasses

Dias HM, Sagawa GYA, Torres-Rodriguez VJ, et al.

Understanding orthologous and homeologous relationships among genes informs how evolution and artificial selection have shaped plant genomes of related species to adapt to different niches and produce diverse phenotypes. Grasses are ecologically and economically important …

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Bioinformatics
Full text 2026

Streptococcus didelphis infection in free-ranging white-eared opossum (Didelphis albiventris) and Brazilian common opossum (Didelphis aurita): pathology, microbiologic, and genomic characterization

Santos DOD, Castro YG, Vieira AD, et al.

Marsupials of the genus Didelphis are highly adapted to urban environments and are widely distributed in the Americas. Streptococcus didelphis is a bacterium that has been isolated from, and associated with disease, in the Virginia …

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Bioinformatics
Full text 2025

Genomics in Epidemiology and Disease Surveillance: An Exploratory Analysis

Tiwari S, Dhakal T, Kim BJ, et al.

Genomics has revolutionized epidemiology and disease surveillance by providing powerful tools for identifying, tracking, and analyzing pathogens at the molecular level. This exploratory analysis examines the integration of genomic with traditional epidemiological approaches, highlighting the …

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Bioinformatics
Full text 2026

The Role of Genomics in Advancing and Standardising Bacteriophage Therapy

Abdraimova N, Shitikov E, Kornienko M.

Bacteriophage therapy, which employs bacterial viruses to selectively eliminate pathogenic bacteria, has re-emerged as a promising strategy in the face of increasing antimicrobial resistance. However, its widespread clinical implementation is constrained by concerns regarding safety, …

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Bioinformatics
Full text 2025

Structured RDF dataset for genomic feature extraction and detection of biotechnological microorganisms of the <i>Burkholderia</i> genus

Osuna-González R, De Ita Luna G, Valdovinos-Rosas RM, et al.

The current dataset has been built from 200 genomes of <i>Burkholderia</i> genus microorganisms in GenBank Flat File (GBFF) format, with information obtained from the National Center for Biotechnology Information (NCBI). Python scripts were developed to …

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Bioinformatics
Full text 2026

Successful experience with high-risk and family screening for Fabry disease in Ninghai County, Zhejiang Province, Eastern China: genotype‒phenotype analysis of the GLA IVS4 + 919G &gt; A variant

Ge Z, Mao J, Dai Z, et al.

BACKGROUND: Fabry disease is a rare and non-specific disease that is difficult and expensive to diagnose. This study aimed to investigate the clinical phenotypes and genetic characteristics of patients with Fabry disease characterised by the …

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Bioinformatics
Full text 2026

Pembrolizumab and Paclitaxel in Patients with HR+/HER2- Breast Cancer with HER2-Enriched or Basal-like Subtypes

Conte B, Brasó-Maristany F, Pascual T, et al.

<h4>Purpose</h4>Hormone receptor-positive (HR+), HER2-negative (HER2-) metastatic breast cancer (mBC) is biologically distinct from early-stage disease, with a higher prevalence of genomically defined nonluminal subtypes, particularly the HER2-enriched (HER2-E) and basal-like subtypes. These tumors are highly …

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Bioinformatics