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Antimicrobial resistance (AMR) is one of the most urgent health threats of the 21st century. Surveillance is needed to enable timely interventions, close knowledge gaps, and anticipate long-term trends. Current frameworks rely heavily on clinical …
Read PDFThe crisis of antimicrobial resistance (AMR) is escalating while the antibiotic pipeline remains stagnant. Our bibliometric analysis of eight decades of literature reveals a critical imbalance: research on AMR has grown, yet fundamental research on …
Read PDFAntibiotic resistance continues to erode the effectiveness of modern medicine, creating an urgent demand for rapid and reliable diagnostic solutions. Conventional diagnostic approaches, including culture-based susceptibility testing, remain the clinical reference standard but are constrained …
Read PDFHepatic alveolar echinococcosis (HAE), a life-threatening zoonosis, poses formidable surgical challenges when involving critical vasculature. Herein, we reported the periprocedural management dilemmas in radical resection for advanced HAE. A 58-year-old female visited the outpatient department …
Read PDFThe continued emergence of pathogens, whether novel, re-emerging, or engineered, poses a persistent global biosecurity and public health challenge. Recent outbreaks, including COVID-19, Lassa fever, Marburg virus, mpox, and avian influenza, underscore the urgent need …
Read PDF<b>Background:</b> Polyphenols interact bidirectionally with the gut microbiota and may influence short-chain fatty acid (SCFA) production, yet evidence from human randomized controlled trials (RCTs) has not been comprehensively synthesized. <b>Objectives:</b> In this systematic review and …
Read PDFHere, we report the complete genome sequencing of a new <i>Mycobacterium</i> sp. nov. from a compromised Japanese individual with hematological malignancy. This will represent the essential data for future phylogenetic and comparative genome studies and …
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Read PDFPetroleum hydrocarbon pollution is an escalating global issue, particularly in developing countries, where it has attracted significant attention from researchers focusing on bioremediation, monitoring and sustainability. This study utilised metagenomics to investigate the bacterial community's …
Read PDFAquatic environments are key reservoirs and dissemination pathways of antimicrobial resistance (AMR). However, current water-based surveillance remains fragmented and inefficient for the timely detection of emerging threats. Integrating artificial intelligence with embedded metadata provides a …
Read PDFNon-typhoidal <i>Salmonella</i> (NTS) and thermotolerant <i>Campylobacter</i> remain leading causes of bacterial gastroenteritis worldwide, with a disproportionate burden in low- and middle-income regions. This updated review synthesizes current evidence on their epidemiology, antimicrobial resistance (AMR) dynamics, …
Read PDFMicrobial biodegradation represents a promising approach to addressing global plastic pollution, yet the metabolic pathways and environmental origins of polymer-degrading microorganisms remain incompletely characterized. This review synthesizes current knowledge on biodegradation mechanisms across major polymer …
Read PDFThe human gut microbiota, a dynamic and highly complex ecosystem comprising bacteria, archaea, fungi, viruses, and their collective genetic material, has emerged over the past two decades as one of the most intensively studied determinants …
Read PDFCrohn's disease (CD) activity and postoperative recurrence significantly affect patients' quality of life, highlighting the need for new treatment and prevention strategies. We read with interest Boronat-Toscano <i>et al</i>'s study on <i>Dialister</i>-driven succinate accumulation in …
Read PDFMicrobial and enzymatic strategies for per- and polyfluoroalkyl substance (PFAS) transformation are receiving increasing attention, but remain at an early stage of scientific development. This review evaluates the limited but emerging evidence for microbially mediated …
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