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Cross-kingdom microbial symbioses, such as those between algae and bacteria, are key players in biogeochemical cycles. The molecular changes during initiation and establishment of symbiosis are of great interest, but quantitatively monitoring such changes can …
Read PDF<h4>Introduction</h4>Sudden Unexpected Death in Epilepsy (SUDEP) refers to the unexplained, sudden death of individuals with epilepsy, and its incidence is closely linked to the severity and duration of seizures. This study aimed to identify plasma …
Read PDF<h4>Background</h4>The patients with intrahepatic cholangiocarcinoma (iCCA) are highly susceptible to recurrence after radical resection, while predicting recurrence remains challenging. Adjacent-to-tumor tissues (ATTs), as the main microenvironment for postoperative recurrence, exhibited superior predictive value for recurrence …
Read PDFSelenium (Se) is an essential trace element for chickens that develops, through selenoproteins, important physiological functions. Although selenogen expression and Western blot analyses provided valuable information, there is a lack of information about the serum …
Read PDF<h4>Rationale</h4>Human hair shafts have received increased research interest owing to their easy accessibility and potential as a window for human health. Because the most abundant component in hair is protein, proteomics is a promising tool …
Read PDF<h4>Background</h4>There is an urgent need for the development of innovative diagnostic and therapeutic strategies in bladder cancer (BlCa) management, due to its significant incidence, mortality, and morbidity. Extracellular vesicles (EVs) constitute promising candidates as biomarkers, …
Read PDF<h4>Background</h4>Cardiomyopathies encompass a spectrum of myocardial disorders often attributed to underlying genetic mutations. However, genotype-phenotype discordance where the genetic profile does not align with the expected clinical presentation poses significant diagnostic, prognostic, and therapeutic challenges.<h4>Objective</h4>To …
Read PDFMultidrug-resistant <i>Salmonella</i> has been classified as a pathogen of high priority. However, limited or mixed-quality studies reported multidrug-resistant <i>Salmonella</i> strains from pediatric patients. The study aimed to investigate the prevalence, serotypes, antimicrobial characteristics, and plasmid …
Read PDFAnnotation of genes and transcripts is a key prerequisite for understanding the information that is encoded in newly sequenced genomes. One source of information suited for this purpose is RNA-seq data mapped to the respective …
Read PDF<h4>Background</h4>Foetal chromosomal abnormalities are identified as one of the leading causes of adverse pregnancy outcome in pregnancies that are referred on suspicion of structural abnormalities in the foetus. While various types of genomic analyses can …
Read PDFWe report on the complete genome sequence of the rhizobacterium <i>Paenibacillus</i> sp. PK1-4R. This might be a new species within the genus <i>Paenibacillus</i>, as evidenced by the taxonomic classification using the TYGS web server. It …
Read PDFA key mutation for generating transgenics in <i>Tribolium castaneum</i> is <i>vermilion <sup>white</sup></i> ( <i>v <sup>w</sup></i> ). <i> v <sup>w</sup></i> is a deletion that removes most of the <i>vermilion</i> locus, but the upstream breakpoint has not been …
Read PDFSomatic structural variants (SVs) are the predominant source of cancer driver mutations and play a critical role in oncogenesis. Comprehensive characterization of somatic SVs is critical for elucidating the mechanisms underlying tumorigenesis and for identifying …
Read PDF<i>Mesoterricola</i> strains MK458 and JemC181 are anaerobic bacteria within the phylum <i>Acidobacteriota</i>, isolated from sediment and paddy soil, respectively. Here, we report their complete genomes, ranging from 4.76 to 5.18 Mb in size, with G …
Read PDFClass D carbapenemase-producing Enterobacteriaceae have spread globally in recent decades. The increasing detection of novel variants, often differing by amino acid substitutions or deletions in the β5-β6 loop of OXA-48 or OXA-372 lineages, indicated ongoing …
Read PDFBACKGROUND: Satellite DNAs (satDNAs) can arise from diverse genomic regions, but determining their precise origin remains a major challenge. A previous study reported the colocalization of the As51 satDNA and the 45S ribosomal DNA (rDNA) …
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