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The analysis of single-copy core genes, common to most members of a clade, is important for key tasks in biology including phylogenetic reconstruction and assessing genome quality. Core genes are traditionally identified by the analysis …
Read PDF<b>Objectives</b>: <i>Trichophyton indotineae</i>, a dermatophyte closely related to <i>T. interdigitale</i> and <i>T. mentagrophytes</i>, is of growing concern due to its high terbinafine resistance and widespread presence in India. Its emergence in Europe calls for enhanced …
Read PDF<h4>Summary</h4><i>ExRec</i> (Exclusion of Recombined DNA) is a dependency-free Python pipeline that implements the four-gamete test to automatically filter out recombined DNA blocks from thousands of DNA sequence loci. This procedure helps all loci better meet …
Read PDFAcanthoic acid, a diterpene isolated from the root bark of <i>Acanthopanax koreanum</i> Nakai, possesses diverse pharmacological activities, including anti-inflammatory, anti-diabetic, gastrointestinal protection, and cardiovascular protection. This study is the first to investigate the egg-hatching rates …
Read PDFPlastid genomes (plastomes) in green algae display remarkable variation in size and structure, yet comprehensive species and strain-level analyses remain rare. Here, we present a detailed plastome comparison across 29 strains of nine nominal species …
Read PDFThe Leishmaniinae subfamily of the Trypanosomatidae contains both genus <i>Zelonia</i> (monoxenous) and <i>Endotrypanum</i> (dixenous). They are amongst the nearest known relatives of <i>Leishmania</i>, which comprises many human pathogens widespread in the developing world. These closely …
Read PDF<i>Roscoea</i> is an alpine or subalpine genus from the pan-tropical family Zingiberaceae, which consists of two disjunct groups in geography, namely the "Chinese" clade and the "Himalayan" clade. Despite extensive research on the genus, <i>Roscoea</i> …
Read PDFA novel Gram-stain-positive, black-pigmented bacterium, designated as WL48A <sup>T</sup>, was isolated from the surface of badland sedimentary rock in the Red Desert of Wyoming and characterized using a polyphasic taxonomic approach. Good growth occurred at …
Read PDF<i>Rhododendron farrerae</i> Tate ex Sweet 1831 is a species of ornamental plant found in southern China. In the present study, the complete chloroplast genome of <i>R. farrerae</i> was sequenced. The genome was 149,453 bp in …
Read PDF<i>Dalbergia sissoo</i> is one of the most economically important trees in forestry, agroforestry, and horticulture. This tree species is severely threatened by dieback. Widespread dieback outbreaks and infestations have drastically destroyed billions of <i>D. sissoo</i> …
Read PDFMagnetotactic bacteria (MTB) biomineralize intracellular, membrane-enclosed magnetite or greigite nanocrystals (magnetosomes). How magnetosome gene clusters (MGCs) control magnetosome morphology and evolve across lineages remains central to reconstructing the history of magnetotaxis. Here, we report five …
Read PDFDermatophytosis is one of the most common superficial infections of the skin affecting nearly one-fifth of the world population at any given time. With nearly 30% of worldwide terbinafine-resistance cases in Trichophyton mentagrophytes/Trichophyton interdigitale and …
Read PDF<h4>Background</h4>The lifetime prevalence of acute urticaria is approximately 20%. Although electroacupuncture (EA) has been investigated as an adjunctive treatment for urticaria, the molecular mechanisms underlying these effects remain elusive. Passive cutaneous anaphylaxis (PCA) serves as …
Read PDFUbiquitination serves as a key regulatory mechanism in nearly all cellular processes, though it was originally identified as a post-translational modification that targets proteins for degradation. Accordingly, these two molecular events have since been tightly …
Read PDFEwing sarcoma (EWS), a rare pediatric bone tumor, poses unique therapeutic challenges due to its distinct microenvironment and limited molecular understanding. To gain a comprehensive molecular and functional view of the tumors in their microenvironment, …
Read PDF<h4>Background</h4>Host cell proteins (HCPs) are process-related impurities that must be monitored in biopharmaceutical products due to their potential impact on product quality and patient safety. Targeted LC-MS/MS approaches such as multiple reaction monitoring (MRM) enable …
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