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Full text 2025

ASTER: A Package for Large-Scale Phylogenomic Reconstructions

Zhang C, Nielsen R, Mirarab S.

Many algorithms are available for inferring species trees from various input types while accounting for gene tree discordance. Several quartet-based species tree inference methods, collectively known as the ASTRAL family, are based on similar ideas …

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Bioinformatics
Full text 2025

TreeHub: a comprehensive dataset of phylogenetic trees

Wu P, Cao Y, Yang J, et al.

Phylogenetic relationships are crucial for solving various biological questions, serving as a fundamental knowledge in biology. However, the application of phylogenetic trees has been limited by inadequate coverage of updated published phylogenies and the scarcity …

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Bioinformatics
Full text 2026

Are interphylum spiralian relationships resolvable?

Serra Silva A, Telford MJ.

The phyla making up the major animal clade of Spiralia have been clear since the advent of molecular phylogenetics; the relationships between these spiralian phyla have not. The lack of consensus over the relationships between …

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Bioinformatics
Full text 2025

Advances and challenges in understanding evolution through genome comparison: meeting report of the European Molecular Biology Organization (EMBO) lecture course "Evolutionary and Comparative Genomics"

Gavriilidou A, Stamatakis A, Kupczok A, et al.

This perspective outlines emerging trends, key challenges, and future opportunities in evolutionary and comparative genomics. Our starting point are the topics presented at the 2024 EMBO Early Career Lecture Course "Evolutionary and Comparative Genomics", which …

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Bioinformatics
Full text 2025

Identification of pandemic ST147, ESBL-type β-lactamases, carbapenemases, and virulence factors in Klebsiella pneumoniae isolated from southern Peru

Aguilar-Ancori EG, Marin-Carrasco M, Campo-Pfuyo LI, et al.

Multidrug-resistant Klebsiella pneumoniae (MDR K. pneumoniae) is a significant pathogen associated with nosocomial infections, often leading to high morbidity and mortality. This resistance is largely due to the efficient horizontal transfer of mobile genetic elements …

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Bioinformatics
Full text 2026

Climatic and geological drivers of diversity in Iranian Barbels lineage (Cypriniformes: Cyprinidae: Barbinae and Torinae): An integrative taxonomic perspective

Khoshnamvand H, Abdoli A, Ahmadzadeh F, et al.

Iranian Barbel taxonomy and evolutionary history (Cyprinidae: Barbinae and Torinae) remain contentious due to overlapping morphological traits and limited molecular data. This study applies an integrative taxonomic framework to elucidate species boundaries, phylogenetic relationships, and …

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Bioinformatics
Full text 2026

Construction and Validation of Multi-Omics Predictive Models for Colorectal Cancer Using Machine-Learning Approaches

Lu Z, Li X, Liang Z, et al.

<h4>Objective</h4>To construct and externally validate a multi-omics nomogram that uses only routine clinicopathological variables to predict tumor mutational burden (TMB), microsatellite instability (MSI), NTRK/PIK3CA mutation status and overall survival (OS) in colorectal cancer (CRC).<h4>Methods</h4>TCGA data …

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Bioinformatics
Full text 2025

UnFATE: A Comprehensive Probe Set and Bioinformatics Pipeline for Phylogeny Reconstruction and Multilocus Barcoding of Filamentous Ascomycetes (Ascomycota, Pezizomycotina)

Ametrano CG, Jensen J, Lumbsch HT, et al.

The subphylum Pezizomycotina (filamentous ascomycetes) is the largest clade within Ascomycota. Despite the importance of this group of fungi, our understanding of their evolution is still limited due to insufficient taxon sampling. Although next-generation sequencing …

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Bioinformatics
Full text 2026

&lt;i&gt;Camphora officinarum&lt;/i&gt; (Syn. &lt;i&gt;Cinnamomum camphora&lt;/i&gt;): Botany, Phytochemistry, Biological Activities, Agro-Industrial Applications, and Biotechnology

Shah K, Dai W, Shen Q, et al.

<i>Camphora officinarum</i> (syn. <i>Cinnamomum camphora</i>) is an ecologically, medicinally, and economically important tree species widely known for its essential oils (EOs), timber, and long history of use in traditional medicine. In recent years, renewed interest …

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Bioinformatics
Full text 2026

Applying Target Capture Sequencing to Unravel the &lt;i&gt;Anthurium&lt;/i&gt; Section &lt;i&gt;Pachyneurium&lt;/i&gt; (Araceae), with Emphasis on Brazilian Species

Camelo MC, Pappas GJ, Silva MC, et al.

<i>Anthurium</i> (Araceae) is one of the most species-rich Neotropical genera, yet its infrageneric classification remains unresolved. This study tests the monophyly of the morphologically defined <i>Anthurium</i> sect. <i>Pachyneurium</i> diagnosed by rosulate habit, involute prefoliation, and …

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Bioinformatics
Full text 2025

Genome-wide phylogeny reshapes our understanding of the evolution of deep-sea dragonfishes, bristlemouths, viperfishes, and allies (Stomiiformes)

Chang S, Heiple Z, Hays D, et al.

<h4>Background</h4>The evolutionary relationships within Stomiiformes, a diverse order of deep-sea fishes dominating the mesopelagic and bathypelagic zones, remain contentious due to conflicting morphological and molecular evidence. These fishes, comprising 464 species across four traditionally recognized …

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Bioinformatics