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Full text 2026

<i>StrainCascade</i>: An automated, modular workflow for high-throughput long-read bacterial genome reconstruction and characterization

Jordi SBU, Baertschi I, Li J, et al.

Long-read sequencing offers unprecedented opportunities for high-resolution bacterial genome reconstruction, yet fragmented bioinformatics workflows hinder biological insights. <i>StrainCascade</i> addresses this gap by providing a fully automated, modular pipeline that integrates genome assembly, accurate annotation, and …

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Bioinformatics Genome Assembly Nanopore Sequencing
Full text 2026

Efficient lossless compression of nanopore sequencing signals

Castelli R, González T, Torrado R, et al.

<h4>Motivation</h4>Efficient data compression is crucial for reducing storage and transmission costs associated to vast volumes of nanopore raw sequencing data. Surpassing the state-of-the-art compression performance has been challenging, and all recent progress in this direction …

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Bioinformatics Nanopore Sequencing
Full text 2026

Complete genome sequence of sorbitol-fermenting, &lt;i&gt;β&lt;/i&gt;-glucuronidase-positive, non-motile &lt;i&gt;E&lt;/i&gt;. &lt;i&gt;coli&lt;/i&gt; O157:H7 isolated from clinical stool specimen

Hwang H, Orth M, Plumb M, et al.

We report the complete genome of a sorbitol-fermenting, <i>β</i>-glucuronidase-positive, non-motile <i>Escherichia coli</i> O157:H7 isolated from a human stool sample. The genome consisted of a 5,487,050-bp circular chromosome and a 79,741-bp F-like plasmid.

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Bioinformatics