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Full text 2026

Investigation of Pharmacogenomic Variants in the CYP (P450) Family in Native American Populations of the Brazilian Amazon

de Freitas LM, Marcellino JCR, de Moraes FCA, et al.

The cytochrome P450 (CYP) enzyme superfamily is essential for xenobiotic metabolism, detoxification pathways, and the regulation of cellular homeostasis. Genetic variability in CYP genes, together with environmental factors, contributes substantially to interindividual and interethnic differences …

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Bioinformatics
Full text 2026

A turn-on fluorescent nucleoside enabling sequence-insensitive DNA labeling

Li J, Dai Z, He L, et al.

Fluorescent nucleobase analogs (FBAs) are valuable tools for studying nucleic acid structure and dynamics. However, their utility is often limited by substantial fluorescence quenching upon incorporation into oligonucleotides and variable brightness influenced by neighboring bases. …

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Bioinformatics
Full text 2026

High acceptability of a national platform for public health genomic data sharing and surveillance in Australia: a mixed methods study

McEwan C, Eghrari D, Ferdinand AS.

<h4>Background</h4>Pathogen genomics has increasingly been integrated into infectious disease surveillance, outbreak detection, and response globally. However, formal evaluation of pathogen genomic surveillance systems has been a major gap. In Australia, the AusTrakka platform was established …

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Bioinformatics
Full text 2026

Knowledge, attitudes, and training on genetic testing among public health professionals and students in the United Arab Emirates: a qualitative study

Elhadi YAM, Elkonaisi I, Alneyadi M, et al.

<h4>Background</h4>As genetic testing becomes increasingly relevant to precision public health, understanding the preparedness of the public health workforce is essential. In the United Arab Emirates (UAE), national initiatives such as the Emirati Genome Program are …

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Bioinformatics