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Full text 2026

WASTER: Practical de novo Phylogenomics from Low-coverage Short Reads

Zhang C, Nielsen R.

The advent of affordable whole-genome sequencing has spurred numerous large-scale projects aimed at inferring the tree of life, yet achieving a complete species-level phylogeny remains a distant goal due to significant costs and computational demands. …

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Bioinformatics Genome Assembly
Full text 2026

Whole-genome sequencing and annotation of probiotic <i>Bacillus amyloliquefaciens</i> COFCAU_P1

Choudhury TG, Khan MIR, Tripathy PS, et al.

<i>Bacillus amyloliquefaciens</i> COFCAU_P1, an autochthonous probiotic from <i>Labeo rohita</i>, was genome sequenced (Illumina NovaSeq; GenBank JBHEQH000000000). Its 4.09 Mb genome encodes 4,351 genes linked to stress tolerance, nutrient utilization, antimicrobial defense, enzymes, and immunomodulation. Phylogenomics …

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Bioinformatics
Full text 2026

Evidence of introgression amid phylogenetic conflict in Brachyotum, a plant radiation from the Tropical Andes

Paredes-Burneo D, Bedoya AM, Michelangeli FA, et al.

<h4>Premise</h4>The species-rich flora of Tropical Andes underwent multiple rapid and recent diversifications, yet resolving their evolutionary histories remains challenging despite increasing phylogenomic data. Here, we examined phylogenomic conflict in Brachyotum (Melastomataceae) to identify sources preventing …

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Bioinformatics
Full text 2026

A Practical Guide for Harnessing Phylogenomics in Biocontrol: Accounting for Topological Uncertainty and Phylogenetic Distance in the Centrifugal Phylogenetic Method and Beyond

Chen SH, Rafter M, Gooden B, et al.

In the genomic era, phylogenomics is playing an increasingly important role in biological control research for prioritising species in host specificity testing, species delimitation, and elucidating the origins of introduced species. This paper outlines key …

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Bioinformatics
Full text 2026

The Possible Significance of Proteomics in Understanding Molecular Mechanisms of Progressive Supranuclear Palsy, Corticobasal Degeneration, Multiple System Atrophy, and Dementia with Lewy Bodies

Madetko-Alster N, Otto-Ślusarczyk D, Struga M, et al.

Atypical Parkinsonisms are a diverse group of diseases associated with multiple pathologies, including synucleinopathies and tauopathies. Atypical Parkinsonisms include progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, and dementia with Lewy bodies. The examination of …

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Bioinformatics