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3689 results

Full text 2025

Genomic Epidemiology of ESBL- and Carbapenemase-Producing Enterobacterales in a Spanish Hospital: Exploring the Clinical-Environmental Interface

Martínez-Álvarez SA, Asencio-Egea MÁ, Huertas-Vaquero M, et al.

Antimicrobial resistance (AMR), particularly due to extended-spectrum β-lactamases (ESBLs) and carbapenemases (CPs), poses a critical threat to global health. This study aimed to characterize the molecular epidemiology, resistance profiles, and genomic features of ESBL- and …

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Bioinformatics
Full text 2025

Phylogenomics of North American cybaeid spiders (Araneae, Cybaeidae), including the description of new taxa from the Klamath Mountains Geomorphic Province

Hedin M, Ramírez MJ, Monjaraz-Ruedas R.

The systematics of humble-in-appearance brown spiders ("marronoids"), within a larger group of spiders with a modified retrolateral tibial apophysis (the RTA Clade), has long vexed arachnologists. Although not yet fully settled, recent phylogenomics has allowed …

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Bioinformatics
Full text 2026

The distribution and evolution of muscarine and the ibotenic acid biosynthetic gene cluster within the genus <i>Amanita</i> section <i>Amanita</i> revealed by phylogenomics

Su YT, He ZM, Yang YZ, et al.

Numerous severe cases of neurotoxic mushroom poisoning worldwide are caused by ibotenic acid and muscimol produced by specific species belonging to section Amanita of the genus <i>Amanita</i>. Recent studies have demonstrated that both toxins are …

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Bioinformatics
Full text 2025

Indirubin-3'-oxime as a dual-action agent: mitigating heat-induced male infertility in <i>Drosophila melanogaster</i> and inhibiting soluble epoxide hydrolase

Phong NV, Kim HS, Zhao Y, et al.

This study investigated the potential of the indirubin-3'-oxime (I3O) compound to mitigate temperature-induced male infertility in <i>Drosophila melanogaster</i>. Elevated temperatures significantly reduced egg-hatching rates, but I3O supplementation improved these rates, suggesting it can partially restore …

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Bioinformatics
Full text 2026

New moss taxa from Eastern Himalaya: Plastid genomics supports the establishment of Scabridentaceae fam. nov. and the description of &lt;i&gt;Scabridens gaochienii&lt;/i&gt; sp. nov. (Hypnales, Bryophyta)

Huang WZ, Liu YS, Ma XY, et al.

The Himalayas represent a globally significant biodiversity hotspot, yet bryophyte diversity remains insufficiently explored, especially in some inaccessible areas. During recent field surveys in Motuo County, Xizang, China, we collected an unusual moss species resembling …

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Bioinformatics
Full text 2026

AliFilter: a machine learning approach to alignment filtering

Bianchini G, Zhu R, Cicconardi F, et al.

Multiple sequence alignments are a crucial step in many bioinformatic and computational biology analyses, from protein structure and function prediction to the inference of phylogenetic trees. However, highly divergent sequence alignments often contain a significant …

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Bioinformatics
Full text 2025

Phylogenomics, evolution and origin of multidrug-resistant &lt;i&gt;Acinetobacter baumannii&lt;/i&gt; ST15

Abu Sabah E, Tobin LA, Lebreton F, et al.

We studied the genomic evolution and transmission dynamics of multidrug-resistant ST15 (Institut Pasteur scheme) <i>Acinetobacter baumannii</i>, examining resistance gene acquisition, clonal diversification, geographic distribution and origin of this high-risk clone. One hundred and fifty-two (<i>n</i>=152) …

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Bioinformatics