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In October 2024, a putative novel species, belonging to the genus <i>Rossellomorea</i>, designated as strain H39_3, was isolated using Luria-Bertani medium from surface water representing station H39, located on the Hindon River, in close proximity …
Read PDFBACKGROUND: Short tandem repeats (STRs) are repetitive DNA sequences with 1–6 nucleotide repeat units, exhibiting high polymorphism due to varying repeat counts. STRs are more variable than SNPs and can cause genetic disorders. With population-scale …
Read PDFCreeping bentgrass (Agrostis stolonifera) is a widely used cool-season turfgrass valued for its fine texture and ability to form dense, uniform turfs. However, its complex allotetraploid genome and high repetitive content have posed challenges for …
Read PDFHuman embryonic stem cell (hESC) neural differentiation involves extensive APA; however, reliance on short-read sequencing in prior studies has offered only a limited view of its complexity and dynamic regulation. Here, we integrated Oxford Nanopore …
Read PDFOBJECTIVE: Onygena corvina is a non-pathogenic, saprophytic fungus that colonizes feathers, hooves, and hair, and represents a valuable source of keratin-degrading enzymes. The only genome assembly of O. corvina available to date was obtained for …
Read PDF<h4>Background</h4>The largemouth bass (Micropterus salmoides, LMB), a globally significant aquaculture species, exhibits pronounced growth dimorphism between the sexes, yet the genetic basis of its sex determination remains unresolved. While published genomes exist, gaps, misassemblies, and …
Read PDFEndophytic fungi are increasingly recognized as pivotal contributors to plant secondary metabolism, often synthesizing bioactive compounds like those produced by their hosts. We report the first complete genome sequence for <i>Pithoascus kurdistanensis</i>, a novel endophyte …
Read PDFDeep intronic FGF14 repeat expansions have been identified as a frequent genetic cause of late-onset cerebellar ataxias, explaining ≤30% of patients. Interruptions between repeats have previously been identified to impact the penetrance in other repeat …
Read PDF<i>Pediococcus pentosaceus</i> TOKAI 759m is a Gram-positive bacterium isolated from rice in Japan. Our previous study demonstrated that this strain is a promising starter culture for soy milk yogurt due to its various beneficial properties. …
Read PDFIn this comment, we re-evaluate the proposal of <i>Aeromonas oralensis</i> as a novel species by Mashzhan et al. (2025) [...].
Read PDFWhole-genome sequencing (WGS) is emerging as a valuable tool for antimicrobial resistance (AMR) surveillance, yet implementation in low-resource settings remains limited by prohibitory costs and infrastructure constraints. Oxford Nanopore Technologies (ONT) offers portable sequencing platforms …
Read PDF<h4>Background</h4>Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that has caused multiple widespread outbreaks and poses a significant public health threat. Recently, CHIKV outbreaks were reported in Guangdong Province, China. However, genomic data and information on …
Read PDFWater quality assessment is critical for determining the suitability of water resources for human consumption. In Santa Marta, northern Colombia, limited access to potable water and sewage systems, along with poor treatment infrastructure, poses a …
Read PDFFast and accurate genetic subtyping of pathogens is required to respond appropriately to biological events caused by natural outbreaks or bioattacks involving anthrax. In this study, we developed and validated a culture-free genotyping method that …
Read PDF<i>Leifsonia</i> sp. McL0608, isolated from <i>Pinus radiata</i> forest soil in New Zealand, has a complete 4.2 Mb circular genome assembled from Nanopore reads. Genome annotations identified 3,942 coding sequences and predicted biosynthetic pathways for alkanes, …
Read PDF<h4>Topic</h4>Inherited retinal dystrophies (IRDs) encompass a group of phenotypically and genetically heterogeneous disorders leading to progressive visual impairment. The advent of next-generation sequencing (NGS) has substantially improved genetic diagnosis rates; however, approximately 30% of IRD …
Read PDFAlternative lengthening of telomeres (ALT) is a recombination-based pathway enabling cancer cells to maintain telomeres. ALT establishment remains poorly understood due to difficulties identifying its molecular steps. Here, using Oxford Nanopore sequencing and computational modeling, …
Read PDF<h4>Background</h4>The RNA virosphere's extensive diversity and its role in emerging infectious diseases underscore the importance of non-targeted sequencing for identifying unknown or rare pathogens, including co-infections. However, enriching low-abundance viral sequences in RNA metaviromics, particularly …
Read PDF<i>Burkholderia pseudomallei</i> is a saprophytic environmental bacterium and the causative agent of melioidosis, a serious opportunistic infection in tropical regions, including northern Australia. Infection occurs following environmental exposure via percutaneous inoculation, ingestion, or inhalation; however, …
Read PDFWhole genome amplification (WGA), and in particular multiple displacement amplification (MDA), has become a key technique for genomic sequencing of microscopic organisms, yet it introduces artefacts such as palindromic (inverted chimeric) reads that may compromise …
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