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<h4>Background</h4>Syndromic forms of obesity are uncommon, complicated illnesses that include early-onset obesity along with other clinical characteristics such as organ-specific abnormalities, dysmorphic symptoms, and intellectual incapacity. These syndromes frequently have a strong genetic foundation, involving …
Read PDF<h4>Summary</h4>The vast amount of publicly available genomic data requires analysis and visualization tools. Here, we present figeno, an application for generating publication-quality FIgures for GENOmics. Figeno particularly focuses on multi-region views across genomic breakpoints and …
Read PDFTumor-derived circulating cell-free DNA (ctDNA) has emerged as a pivotal biomarker for non-invasive cancer diagnosis, treatment monitoring, and prognostic evaluation. However, its inherently low abundance, high fragmentation, and rapid degradation impose stringent requirements on assay …
Read PDFTimely and accurate detection of Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL)-related fusion gene is essential for treatment decisions. However, due to the complexity of possible gene fusion combinations of Ph-like ALL, current diagnostic workflows …
Read PDFEndogenous viral elements inserted in host genomes are often regarded as inert relics of past infections. Whether they can retain infective potential and contribute to active viral cycles has remained largely unresolved. Here we demonstrate …
Read PDFAdenosine-to-inosine (A-to-I) RNA editing is a major epitranscriptomic mechanism, yet its contribution to non-coding RNA regulation during neurodegeneration is largely unknown. SINE B2 RNAs represent the dominant editing substrates in mice and have been shown …
Read PDFWe present a chromosome-level reference genome for the blind scorpion <i>Belisarius xambeui</i> Simon, 1879 (Belisariidae, Scorpiones). The genome size estimated by flow cytometry (4.32 Gb) closely matches the final assembly size (3.98 Gb). The final …
Read PDFAbies koreana E.H.Wilson is an endangered evergreen coniferous tree that is native to high altitudes in South Korea and susceptible to the effects of climate change. Hybridization and reticulate evolution have been reported in the …
Read PDF<h4>Background</h4>Reference genomes have a wide range of applications, but we are far from a complete genomic picture of the tree of life. We here contribute another piece to the puzzle by providing a high-quality reference …
Read PDFThe cotton seed bug, <i>Oxycarenus hyalinipennis</i> Costa (Hemiptera: Lygaeidae), is an invasive cotton pest detected in California, United States, in 2019. This report details the assembly and annotation of a reference genome for <i>O. hyalinipennis</i>, …
Read PDFAs a group of winged insects (Pterygota) retaining many primitive characteristics, genomic research on mayflies remains highly limited, posing challenges to the study of their origin and evolution. In this study, we present the first …
Read PDF<i>Carex pseudochinensis</i> H. Lév. & Vaniot is an endemic species in Korea and is included in the clade of section <i>Paludosae</i> in the recent classification system. We present the complete mitochondrial genome sequence of <i>C. …
Read PDFWolbachia is an obligate intracellular α-proteobacterium, which commonly infects arthropods and filarial nematodes. Different strains of Wolbachia are capable of a wide range of regulatory manipulations in their diverse hosts, including the modulation of host …
Read PDFThe interactions between powdery mildews (Ascomycota, Erysiphaceae), obligate biotrophic pathogens of many plants, and pycnidial fungi belonging to the genus Ampelomyces, are classic examples of specific mycoparasitic relationships. These interactions are common and finely tuned …
Read PDFHolothuria scabra, a commercially valuable yet ecologically vulnerable tropical holothuroid, has experienced a severe decline in its wild populations, especially in China. Genomic resources are crucial for the development of effective genomic breeding projects and …
Read PDF<h4>Background</h4>Cassava is an important crop for food security in the tropics where its production is jeopardized by several viral diseases, including the cassava mosaic disease (CMD) which is endemic in Sub-Saharan Africa and the Indian …
Read PDFAmphibians of the Afrobatrachia clade represent a major component of sub-Saharan Africa's biodiversity, yet they remain underrepresented in genomic databases. Here, we present the first whole-genome assembly of the Common Reed Frog, Hyperolius viridiflavus viridiflavus …
Read PDFThe Asian longhorned beetle, Anoplophora glabripennis (Motschulsky), and the citrus longhorned beetle, A. malasiaca (Thomson) (Coleoptera: Cerambycidae), represent two globally notorious forest pests whose introductions into North America and Europe have caused extensive damage to …
Read PDFSophora flavescens is a medicinal plant in the genus Sophora of the Fabaceae family. The root of S. flavescens is known in China as Kushen and has a long history of wide use in multiple …
Read PDFThe increasing global burden of antimicrobial resistance (AMR) has been identified as a critical public health crisis, necessitating the development of robust, real-time surveillance frameworks to evaluate AMR dynamics. Sewage surveillance is emerging as a …
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